Diagnóstico laboratorial das meningites bacterianas

Abstract

<p class="MsoNormal" style="text-align: justify; text-indent: 36pt; margin: 0cm 0cm 0pt;"><span style="font-family: 'Times New Roman'; font-size: x-small;">A despeito dos avanços tecnológicos em relação ao diagnóstico, à patogênese e ao tratamento, a meningite bacteriana ainda permanece como importante doença de distribuição mundial, cujo diagnóstico se apoia, principalmente, no exame bacteriológico. Mesmo com o avanço das técnicas moleculares, o diagnóstico microbiológico continua sendo amplamente utilizado e, portanto, merece atenção especial. O objetivo deste trabalho foi realizar um levantamento bibliográfico sobre os principais métodos microbiológicos para o diagnóstico das meningites bacterianas e seus principais agentes causadores, visto que a identificação precisa do agente etiológico permite a correta utilização da terapia farmacológica, o que diminui significativamente os riscos de desenvolvimento de sequelas neurológicas. </span><span style="font-family: 'Times New Roman'; font-size: small; text-indent: 36pt;">Abstract:</span></p><span style="font-size: small;"><span style="font-family: Times New Roman;"><span style="mso-ansi-language: PT-BR;"><p class="MsoNormal" style="text-align: justify; margin: 0cm 0cm 0pt; vertical-align: top;"><span style="color: black; mso-ansi-language: EN;" lang="EN">Despite technological advances in the diagnosis, pathogenesis and treatment, bacterial meningitis still remains an important disease of worldwide distribution in which the diagnosis relies mainly on bacteriological examination. Even with the advances in molecular techniques, microbiologic diagnosis is still widely used and therefore deserves special attention. The aim of this study was a literature review on the main microbiological methods for diagnosis of bacterial meningitis and its main agents, since the precise identification of the agent allows the correct use of drug therapy which significantly reduces the risk of developing neurological sequelae.</span></p></span></span></span>

Serological Detection and Risk Factors Associated with Leptospirosis Infection in Subsistence Pigs in the State of Paraná, Brazil

“…The sera that showed 50% of agglutinated leptospiras under the dark field microscope will be titrated with their respective antigens in a geometric series of dilutions of ratio 2. In the screening, the final titer is given as the reciprocal of the highest dilution at which agglutination occurred (Goris & Hartskeerl, 2014; Santa Rosa, 1970), in which each sample is classified as reactive or non-reactive with the aid of a dark field microscope with phase contrast.…”