Diagnóstico do comprometimento cognitivo vascular: recomendações do Departamento Científico de Neurologia Cognitiva e do Envelhecimento da Academia Brasileira de Neurologia

Barbosa, Breno José Alencar Pires; Neto, José Ibiapina Siqueira; Alves, Gilberto Sousa; Sudo, Felipe Kenji; Suemoto, Cláudia Kimie; Tovar‐Moll, Fernanda; Smid, Jerusa; Schilling, Lucas Porcello; Balthazar, Márcio Luiz Figueredo; Frota, Norberto Anízio Ferreira; Souza, Leonardo Cruz de; Vale, Francisco Assis Carvalho; Caramelli, Paulo; Bertolucci, Paulo Henrique Ferreira; Brucki, Sônia Maria Dozzi; Engelhardt, Eliasz; Chaves, Márcia Lorena Fagundes

doi:10.1590/1980-5764-dn-2022-s104pt

Cited by 2 publications

(1 citation statement)

References 113 publications

(200 reference statements)

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“…In the systematic review with meta-analysis performed by Nielsen & Jørgensen 21 , it was observed that, in low- and middle-income countries, RUDAS results are less affected by schooling levels than MMSE. This observation regarding MMSE has also been found in its comparison with other instruments 44 .…”

Section: Discussionsupporting

confidence: 75%

Normalization of Rowland Universal Dementia Assessment Scale (RUDAS) in Chilean older people

Sepúlveda-Ibarra,

Chaparro,

Marcotti

et al. 2023

Dement. neuropsychol.

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Rowland Universal Dementia Assessment Scale (RUDAS) is a cognitive screening that evaluates older people with low educational levels. In Chile, there are no normative data to assess this population. Objective: To obtain normative data on RUDAS in older Chilean people with up to 12 years of schooling, and to determine whether age and schooling years influence a person’s performance on RUDAS and on the items that constitute it. Methods: A group of cognitively healthy people 60 years old or over, with up to 12 schooling years was evaluated (n=135). Multiple regression models were applied to obtain normative data on RUDAS, according to age and schooling years, and to measure the effects of schooling on different items. Results: Regression analysis showed that none of the items had schooling as a significant predictor, except for the visuoconstruction item. The variables age and schooling explained 12.6% (R^2=0.126) of the RUDAS total score variance. The item visuoconstruction was the most associated with the educational level (OR=1,147). Conclusion: This study showed that RUDAS is a recommended instrument for evaluating older people with low educational levels. However, more studies are needed to prove the validity of the RUDAS on Chilean older people.

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Section: Discussionsupporting

confidence: 75%

Normalization of Rowland Universal Dementia Assessment Scale (RUDAS) in Chilean older people

Sepúlveda-Ibarra,

Chaparro,

Marcotti

et al. 2023

Dement. neuropsychol.

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Risk of neurodegenerative disease or dementia in adults with attention-deficit/hyperactivity disorder: a systematic review

Becker,

Chowdhury,

Tavilsup

et al. 2023

Front. Psychiatry

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Purpose of reviewSeveral psychiatric disorders have been associated with an increased risk of developing a neurodegenerative disease and/or dementia. Attention-deficit/hyperactivity disorder (ADHD), a neurodevelopmental disorder, has been understudied in relation to dementia risk. We summarized existing literature investigating the risk of incident neurodegenerative disease or dementia associated with ADHD.Recent findingsWe searched five databases for cohort, case–control, and clinical trial studies investigating associations between ADHD and neurodegenerative diseases/dementia in May 2023. Study characteristics were extracted by two independent raters, and risk of bias was assessed using the Newcastle Ottawa Scale. Search terms yielded 2,137 articles, and seven studies (five cohort and two case–control studies) ultimately met inclusion criteria. Studies examined the following types of neurodegeneration: all-cause dementia, Alzheimer’s disease, Parkinson’s and Lewy body diseases, vascular dementia, and mild cognitive impairment. Heterogeneity in study methodology, particularly covariates used in analyses and types of ratios for risk reported, prevented a meta-analysis and data were therefore summarized as a narrative synthesis. The majority of studies (4/7) demonstrated an overall low risk of bias.SummaryThe current literature on risk of developing a neurodegenerative disease in ADHD is limited. Although the studies identified present evidence for a link between ADHD and subsequent development of dementia, the magnitude of the direct effect of ADHD on neurodegeneration is yet to be determined and better empirically designed studies are first needed. Furthermore, the mechanism of how or why ADHD is associated with an increased risk of developing a neurocognitive disorder is still unclear and should be explored in future studies.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022348976, the PROSPERO number is CRD42022348976.

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Diagnóstico do comprometimento cognitivo vascular: recomendações do Departamento Científico de Neurologia Cognitiva e do Envelhecimento da Academia Brasileira de Neurologia

Cited by 2 publications

References 113 publications

Normalization of Rowland Universal Dementia Assessment Scale (RUDAS) in Chilean older people

Normalization of Rowland Universal Dementia Assessment Scale (RUDAS) in Chilean older people

Risk of neurodegenerative disease or dementia in adults with attention-deficit/hyperactivity disorder: a systematic review

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