Diagnóstico del cáncer de próstata mediante espectroscopia de resonancia magnética endorectal

Batlle, Josep Comet; Busquets, Joan Carles Vilanova; Obregón, Joaquim Barceló; Genover, A. Maroto; Fernández, Margarita Osorio; Bonet, Eugeni López; Quer, N. Torrent; Dalmau, Miquel Ordis; Vidal, Carles Barceló i

doi:10.4321/s0004-06142006001000003

Arch. Esp. Urol.

2006

DOI: 10.4321/s0004-06142006001000003

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Diagnóstico del cáncer de próstata mediante espectroscopia de resonancia magnética endorectal

Josep Comet Batlle

Joan Carles Vilanova Busquets

Joaquim Barceló Obregón

et al.

Abstract: Resumen.-OBJETIVO: La espectroscopia de resonancia magnética endorectal (RMS) es una nueva técnica de imagen que permite realizar una evaluación más precisa y fiable de la localización y estadiaje del cán

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Cited by 3 publications

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Prostate cancer: diagnostic utility of multiparametric prostate MRI with 3D spectroscopy in the CMDLT January-June 2023

De Freitas,

Burgos

2024

UNOAJ

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The prostate gland secretes citrate, the levels of which vary in benign prostatic hyperplasia and tumors. Multiparametric MRI of the prostate, although sensitive, has limitations in its specificity. Spectroscopy can quantify these cellular metabolites. At the La Trinidad Teaching Medical Center, 46 studies were carried out with 3D spectroscopy in patients referred from the urology service from January to June 2023. The objective was to verify the diagnostic usefulness of 3D spectroscopy with multiparametric Magnetic Resonance of the prostate. The findings in the 3D prostate spectroscopy metabolite map were described, the results of the mpMRI PIRADS score and the metabolite map were analyzed, and the anatomical pathological and 3D spectroscopy results were compared. A 1.5T Philips Anchieva resonator was used with 3D prostate spectroscopy sequences in 36 patients. The metabolites in 3D spectroscopy showed correlation with the suspicious criteria according to SCORE PI-RADS, especially in the suspicious nodular areas. The sensitivity and positive predictive value were 88%, while the specificity and negative predictive value were 96%. However, more studies are needed to obtain more conclusive results.

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Prostate cancer: diagnostic utility of multiparametric prostate MRI with 3D spectroscopy in the CMDLT January-June 2023

De Freitas,

Burgos

2024

UNOAJ

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In Vivo Spectroscopy vis-à-vis Ex Vivo Spectroscopy: Pearls and Pitfalls: Imaging Review

Razak¹,

Gupta²,

Meena³

2017

Mol Biol

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Aims and objective: The objective of this communication is to bring the metabolomics by magnetic resonance (high resolution spectroscopy) to the clinical radiologist and compare the spectroscopy in vivo (NMR spectroscopy used in clinical) with the high resolution spectroscopy ex vivo (magic angle spectroscopy, HR -MORE). S and analyzing differences, advantages and limitations of each technique in different tissues. Review of the topic:In vivo spectroscopy that is usually performed in the clinic is a non-invasive technique that can provide important information for the diagnosis and monitoring of different lesions. The most well-known applications of in vivo spectroscopy today are those carried out by localized 1H spectroscopy, monovoxel or multivoxel (spectroscopic image), brain, prostate or breast. There are other modalities, such as the 31 P or 13ºC spectroscopy, but they are much less frequent and are only carried out in a few specialized centres. Without any doubt, the most widespread clinical use is confined to the central nervous system. Conclusion:The in vivo spectroscopy provides important metabolic information for the diagnosis of different pathologies, non-invasively, however, this technique has certain limitations, such as low spectral resolution, that is, the number of metabolites that can be identified/quantified; which results in low diagnostic specificity.Ex vivo spectroscopy, however, has a spectral resolution and sensitivity far superior to in vivo techniques, which allows detecting a large number of metabolites, and therefore greatly improves its diagnostic capacity. However, we must not forget that it is an invasive technique, since it is based on the analysis of pieces of tissue (biopsies, surgical pieces...) and therefore loses its usefulness in those lesions that are impossible to biopsy. In conclusion, each technique has its added value and its limitations and it is the correct use of them and the combination of them with other diagnostic parameters, where their clinical potential resides.

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Biopsia de próstata dirigida por espectroscopia

et al. 2007

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INTRODUCCIÓNEl cáncer de próstata constituye en la actualidad un grave problema tanto para los varones como para los profesionales de la medicina, bien sean mé-dicos generalistas como especialistas.En la actualidad es infrecuente encontrarnos, en nuestra consulta, con pacientes con enfermedad tumoral prostática evolucionada, aunque desgraciadamente el día a día no nos permita olvidarnos de un pequeño grupo que debuta en esta catastrófica situación. La realidad más frecuente es encontrarnos con pacientes a los que por un motivo u otro se les ha realizado una determinación de PSA (analítica rutinaria, antecedentes familiares, indicación de su pareja, estudio preventivo, etc.), siendo esta anóma-la, motivo de posteriores estudios urológicos que determinarán, según los protocolos asumidos por cada grupo de trabajo, repetición de la exploración física, nuevas determinaciones analíticas y cálculos (PSA, PSA libre, PSA complex, cociente de PSA L/T, densidad de PSA, densidad de PSA de la región transicional, velocidad de PSA, PSA en relación a la edad,

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Diagnóstico del cáncer de próstata mediante espectroscopia de resonancia magnética endorectal

Abstract: Resumen.-OBJETIVO: La espectroscopia de resonancia magnética endorectal (RMS) es una nueva técnica de imagen que permite realizar una evaluación más precisa y fiable de la localización y estadiaje del cán

Cited by 3 publications

References 26 publications

Prostate cancer: diagnostic utility of multiparametric prostate MRI with 3D spectroscopy in the CMDLT January-June 2023

Prostate cancer: diagnostic utility of multiparametric prostate MRI with 3D spectroscopy in the CMDLT January-June 2023

In Vivo Spectroscopy vis-à-vis Ex Vivo Spectroscopy: Pearls and Pitfalls: Imaging Review

Biopsia de próstata dirigida por espectroscopia

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