Diagnostic Value of Serum Biomarker Human Epididymis Protein4 in Ovarian Cancers

Gurashi, Rimaz Elhag; Hummeida, Moawia E.; Abdelaziz, Faisal Galal

doi:10.11648/j.ajlm.20200501.13

Cited by 1 publication

(2 citation statements)

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“…The most common subtype is serous OC. This is similar to previous studies by the Gurashi group reporting 43% of all OCs included in their study are diagnosed at an advanced stage (stage III and IV) and only 15% in early stage (stage II and I) [23].…”

Section: Factors -Urogenital Tuberculosissupporting

confidence: 92%

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Ovarian Cancer in the Sudan - Identifying the Social and Clinical Factors that Prevent an Early Diagnosis

Mohamed¹,

Bature²,

Guinn³

et al. 2021

austiniobstetgynecol

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Ovarian cancer, because it often presents with vague symptoms, is a difficult disease to diagnose at the early stages, especially in developing countries. In Sudan, diagnosis is further complicated by additional factors and challenges. First, as in any developing country, access to treatment, facilities and medical staff is generally lacking. Secondly, Sudan is the second largest country in Africa: its very size presents difficulties for the implementation of a centralized health system. The two tertiary hospitals in or near the capital have long patient waiting lists. The lack of female education in sub-Saharan Africa, together with social and economic issues affecting women, is a further obstacle to disease diagnosis and management. Misdiagnosis, leading to inappropriate treatment, may result from the presence of comorbid diseases such as Tuberculosis (TB), which can mimic ovarian cancer and obstruct early detection. Most patients are identified at the later stages when the complications associated with invasive procedures and conventional chemotherapy make treatment much less effective. The early detection of biomarkers may prove to be a vital tool to indicate targets for immunotherapy treatment. Financial aid may help improve the outcomes for patients with ovarian cancer in the Sudan, assisting with diagnosing and management procedures including training medical staff. Research and development, documentation and updating the statistical register for the whole country are also important requirements for future improvements. Finally, there is a need to promote interdisciplinary work between surgeons and clinical oncologists to optimize international guidelines and protocols in accordance with the facilities available.

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Section: Factors -Urogenital Tuberculosissupporting

confidence: 92%

“…Our findings, as per previous results [23], were that the CT scan and blood tests of CA125 levels were not accurate measures that indicated an OC diagnosis. CA125 was not good marker for OC but still, nothing available is better.…”

Section: Ct Scanning and Ca125 For Oc Diagnosissupporting

confidence: 67%