Diagnostic value of multislice computerized tomography angiography for aortic dissection: A comparison with DSA

Dong, Lu; Li, Chengli; Lv, Wei‐Fu; Ni, Ming; Deng, Kan; Zhou, Chunze; Xiao, Jianghong; Zhang, Zhen‐Feng; Zhang, Xingming

doi:10.3892/etm.2016.3985

Cited by 5 publications

(4 citation statements)

References 17 publications

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“…Therefore, our model could be used for imaging studies of AD, including CTA-based hydrodynamic studies of AD [ 13 , 14 , 15 ]. Our experimental results also suggested that the blood flow velocity in the false lumen of the dissected artery was significantly ( P <0.001) lower than that in the true lumen, which is consistent with previous studies on the flow characteristics of the true and false lumens of ADs [ 12 , 16 ].…”

Section: Discussionsupporting

confidence: 92%

“…In addition, the design of the purse-string suture placed around the aortic incision can reduce the semi-blocking time for the descending aorta to approximately 90 s, greatly reducing the blocking time during surgery and the burden on the heart, lungs, and brain in the experimental dogs, which could improve the success rate of surgery. Considering the 3Rs principles [ 12 ], minimizing invasiveness is also critical to alleviating pain in experimental animals. We also determined the anatomical position of the vagus nerve in the aortic arch.…”

Section: Discussionmentioning

confidence: 99%

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Construction of a canine model with acute type B aortic dissection using a self-made pressure-driven flow device

Liu

Niu

et al. 2023

Exp. Anim.

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A reproducible canine aortic dissection (AD) model is useful for evaluating the performance of novel endovascular treatment devices. Thus, we performed a surgical method for constructing a reproducible Stanford type B AD (TBAD) canine model. Computed tomography angiography was performed 2 h after the modeling procedure to identify the existence of a false lumen, and follow-up imaging was performed 10 d after the procedure using digital subtraction angiography, intravascular ultrasound (IVUS), and color Doppler flow imaging (CDFI) to confirm the stable persistence of the false lumen. The success rate of the modeling operation was 88.8% (16/18). All surviving dogs had distal re-entries (16/16), and the furthest re-entry did not exceed the celiac trunk artery. The number of re-entries in the dogs was 1.50±0.52, and the mean length of the false lumen was 175.37 ± 16.98 mm. IVUS showed that the largest proportion of the false lumen was 84.88 ± 1.27% of the whole lumen. The CDFI showed that the peak systolic velocity in the false lumen (10.89 ± 0.74 cm/s) was significantly slower than that in the true lumen (25.31 ± 1.72 cm/s) (P <0.001). Moreover, the direction of blood flow in the true lumen was consistent, whereas that in the false lumen was disordered.We optimized the traditional surgical method to construct a canine model of TBAD, that improves the success rate of the modeling operation, and designed a novel device to prolong the false lumen. The proposed model have wide implications in evaluating novel endovascular treatment device performance and studying the AD-related hemodynamics.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Construction of a canine model with acute type B aortic dissection using a self-made pressure-driven flow device

Liu

Niu

et al. 2023

Exp. Anim.

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“…In addition to its advantages of convenience, noninvasiveness, and high patient acceptance, MSCTA can more intuitively display the length of arterial vessels, the degree of stenosis, collateral circulation, and perivascular tissue. MSCTA has many image processing methods, and different processing techniques can be selected according to needs, which can provide a variety of rich image data for clinical practice [ 22 ]. In this work, the stenosis of lower extremity arteries can be clearly observed and classified according to the degree of stenosis by selecting maximum density projection, solvent reconstruction, and multiplanar reconstruction technology after MSCTA scanning.…”

Section: Discussionmentioning

confidence: 99%

Multislice Computed Tomography Angiography Imaging Diagnosis of Lower Extremity Arteriosclerosis in Patients with Hypertension and Its Correlation with the Level of High-Sensitivity C-Reactive Protein

Huo

Jiang

Zhang

2022

Computational and Mathematical Methods in Medicine

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The aim of this study was to investigate the relationship between multislice computed tomography (CT) angiography (MSCTA) imaging and high-sensitivity C-reactive protein (hs-CRP) in patients with hypertension and lower extremity arteriosclerosis. 68 hypertensive patients with lower extremity arteriosclerosis were selected as the observation group, and 68 healthy volunteers were selected as the control group to compare the differences in hs-CRP. According to the degree of stenosis, the patients were further divided into five grades: no obvious stenosis, mild stenosis, moderate stenosis, severe stenosis, and occlusion. The correlation between the degree of stenosis and the content of hs-CRP was compared. The changes of hs-CRP content before and after treatment were compared, and the difference of images before and after surgical treatment and the difference of hs-CRP expression in patients with occlusion were compared. Compared with the control group, the content of hs-CRP in the observation group was significantly higher ( P < 0.05 ), and the degree of stenosis was positively correlated with the content of hs-CRP. After two weeks of treatment, the hs-CRP levels of patients with severe stenosis and occlusion were significantly lower than those before treatment ( P < 0.01 ). The level of hs-CRP in patients with occlusion after arterial stent intervention was significantly lower than before, and the images also showed that the blood vessels were significantly expanded. The degree of stenosis in patients with lower extremity arteriosclerosis diagnosed by MSCTA imaging was closely related to the expression of hs-CRP in the patient, and a sustained high concentration of hs-CRP corresponded to a more severe degree of vascular occlusion. In conclusion, the hs-CRP can be used as one of the factors to predict and evaluate the occurrence of cardiovascular and cerebrovascular diseases.

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“…The 2-dimentional (2D) DSA was performed on a GE Innova 3100 system for diagnosis of patients with AD. The images were taken in the anterior, posterior, and oblique 30º projections (Lu et al, 2017). The obtained images were analyzed on the GE Advantage Workstation 4.3.…”

Section: Patientsmentioning

confidence: 99%

Comparison of CT and MRI in imaging diagnosis of aortic dissection

et al. 2022

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Aortic dissection(AD) is a life-threatening disease due to a tear in the intimal layer of the aorta within the aortic wall. To compare diagnostic value and imaging of AD between computed tomography(CT) and magnetic resonance imaging (MRI). 120 AD patients diagnosed were examined with 64-slice CT and 1.5 MRI, the imaging data of true and false lumen, intimal flap, intimal tear, mural thrombus and aortic calcification were compared. The intimal flap rate of CT and MRI was 81.7% and 100%, respectively; The intimal tear rate of CT and MRI was 68.3% and 83.3%, respectively; The rate of mural thrombus in CT and MRI was 26.7% and 54.2%, respectively; The rate of aortic calcification in CT and MRI was 62.5% and 18.3%, respectively; The number of patients with intimal tear lower than 1mm in CT and MRI was 5 and 0, respectively. Both CT and MRI can show the true and false lumen well, but the detection rate of intimal flap, intimal tear and mural thrombosis in MRI is significantly higher than that in CT, and the detection rate of aortic calcification and intimal tear<1mm in CT is higher than that in MRI.

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Diagnostic value of multislice computerized tomography angiography for aortic dissection: A comparison with DSA

Cited by 5 publications

References 17 publications

Construction of a canine model with acute type B aortic dissection using a self-made pressure-driven flow device

Construction of a canine model with acute type B aortic dissection using a self-made pressure-driven flow device

Multislice Computed Tomography Angiography Imaging Diagnosis of Lower Extremity Arteriosclerosis in Patients with Hypertension and Its Correlation with the Level of High-Sensitivity C-Reactive Protein

Comparison of CT and MRI in imaging diagnosis of aortic dissection

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