Diagnostic value of echocardiography combined with serum C-reactive protein level in chronic heart failure

Abstract

Background Chronic heart failure (CHF) is regarded as common clinical heart disease. This study aims to investigate the clinical diagnostic value of echocardiography (Echo) and serum C-reactive protein (CRP) levels in patients with CHF. Methods A total of 75 patients with CHF (42 males, 33 females, age 62.72 ± 1.06 years) were enrolled as study subjects, with 70 non-CHF subjects (38 males, 32 females, age 62.44 ± 1.28 years) as controls. The left ventricular ejection fraction (LVEF), fraction shortening rate of the left ventricle (FS), and early to late diastolic filling (E/A) were determined by Echo, followed by an examination of the expression of serum CRP by ELISA. In addition, the Pearson method was used to analyze the correlation between echocardiographic quantitative parameters (EQPs) (LVEF, FS, and E/A) and serum CRP levels. Receiver operating characteristic (ROC) curve was adopted to evaluate the diagnostic efficacy of EQPs and serum CRP levels for CHF. The independent risk factors for CHF patients were measured by logistics regression analysis. Results The serum CRP level of CHF patients was elevated, the values of LVEF and FS decreased, and the E/A values increased. ROC curve revealed that the EQPs (LVEF, FS, and E/A) combined with serum CRP had high diagnostic values for CHF patients. Logistic regression analysis showed that the EQPs (LVEF, FS, and E/A) and serum CRP levels were independent risk factors for CHF patients. Conclusion Echo combined with serum CRP level has high clinical diagnostic values for CHF patients.

Diagnostic and prognostic value of plasma miR-106a-5p levels in patients with acute heart failure

“…As found in previous research, NT-proBNP and hs-CRP are highly expressed in the serum of HF patients [ 25 , 26 ] and are of great reference value in assisting the diagnosis of AHF [ 6 , 27 ]. Therefore, the Spearman correlation analysis was performed to explore the correlation of plasma miR-106a-5p levels with NT-proBNP and hs-CRP levels in AHF patients.…”

Association between N-terminal pro-B-type natriuretic peptide and clinical outcomes in bedridden patients with stroke: a cross-sectional study

“…Meanwhile, LVEF and FS, which are used to evaluate LV systolic function, and E/A, which is used to evaluate LV diastolic function, were lower in bedridden than in non-bedridden patients. 31 It implies that damage to myocardial tissue and cardiac function was more severe in bedridden than in non-bedridden patients. Apart from stroke-induced myocardial injury and cardiac dysfunction, bed rest can lead to several changes in cardiac structure and function, such as loss of cardiac mass, reduced ventricular diameter, prolonged isovolumetric relaxation time, decreased stroke volume and impaired aerobic capacity, which may contribute to poor outcomes and substantial mortality risk.…”