Diagnostic value of carotid artery ultrasound and hypersensitive C-reactive protein in Type 2 diabetes mellitus patients with acute myocardial infarction in Chinese population

Li, Juan; Wang, Liangliang; Wang, Qian; Xin, Zhaoqin; Liu, Yilin; Zhao, Qinghua

doi:10.1097/md.0000000000012334

Cited by 4 publications

(5 citation statements)

References 20 publications

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“…While in both UA and MI patients, the HsCRP marker could be reported very good indicators for patient's diagnosis, these results agree with (Seyedian et al, 2016) (23) study regarding to UA and agree with (Wang et al, 2020) study (24) which stated that the HsCRP has an important clinical value in the MI diagnosis. Also the present study observed that the HsCRP marker is always significant in the diagnosis between all the groups' combinations, as pointed by the many studies such as (23) , (25) and (24) studies.…”

Section: Discussionsupporting

confidence: 81%

Estimation of HsCRP and Cardiac Troponin I in Ischemic Heart Disease Iraqi Patients

Aadai,

Iqbal,

Mehdi

et al. 2021

Indian Journal of Forensic Medicine & Toxicology

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The present study is an attempt to investigate the changes in serum cardiac troponin (cTn) and Highsensitivity C-reactive protein (HsCRP) markers levels in Iraqi ischemic heart disease (IHD) patients including stable angina (SA), unstable angina (UA) and myocardial infarction (MI) compared to the healthy controls (HC), and to evaluate the importance of the HsCRP between these diseases combination groups from the dignostic point of view, in addition to find a significant correlation between HsCRP level and some IHD risk factors. The IHD's mortality surpass that of every major disease, so it is important that to get such research especially among Iraqi patients. IHD is defined as blood flow reduction to the heart muscle due to build-up of fatty strips (plaque) in the coronary arteries, it exists when the coronary blood flow becomes incapable of both delivering sufficient oxygen (O 2 ) to the myocardium and taking away the carbon dioxide (CO 2 ) from the cells. Collecting the blood samples from one hundred thirty IHD patients (during the period from October 2020 to February 2021) with ages ranged (30-80) years, of both genders, investigated for HsCRP by enzyme linked immune sorbent assay (ELISA) technique and cardiac Troponin (cTn I) by immunochromography method. This study observed that the HsCRP marker is a reliable diagnostic indicator in both MI and UA groups (but not in SA patients), and in all diseases combination groups, and that there was significant correlations between each of the triglyceride level and the hypertension, and the HsCRP marker level, only in the MI group, but not in SA and UA patients.

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Section: Discussionsupporting

confidence: 81%

Estimation of HsCRP and Cardiac Troponin I in Ischemic Heart Disease Iraqi Patients

Aadai,

Iqbal,

Mehdi

et al. 2021

Indian Journal of Forensic Medicine & Toxicology

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“…Hypersensitive C-reactive protein (hs-CRP) is a highly sensitive acute inflammatory protein produced by the liver (5), which may be used as an independent risk factor for predicting adverse cardiovascular events. A number of studies have indicated an increase in serum hs-CRP in patients with AMI (6,7).…”

Section: Introductionmentioning

confidence: 99%

Changes of cardiac troponin I and hypersensitive C‑reactive protein prior to and after treatment for evaluating the early therapeutic efficacy of acute myocardial infarction treatment

Wang

Liao²,

et al. 2019

Exp Ther Med

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The present study aimed to evaluate the utility of the extent of change (C) and change rate (Cr) of cardiac troponin I (cTnI) and hypersensitive C-reactive protein (hs-CRP) prior to and after treatment in evaluating the early therapeutic efficacy of acute myocardial infarction (AMI) treatment. A total of 145 patients with AMI who received regular MI treatment were enrolled in the present study. Patients were divided into the effective group and the ineffective group based on the early therapeutic efficacy. The values of two parameters, namely the serum levels of cTnI and hs-CRP, were collected prior to and after AMI treatment. Data were analyzed by using the t-test, Chi-squared test, logistic regression and receiver operating characteristic (ROC) curve analysis. Compared with those in the ineffective group, the values of cTnI and hs-CRP after treatment [cTnI (post) and hs-CRP (post) ], as well as their C and Cr values, were significantly decreased in the effective group (P<0.01). Furthermore, the positive rates (PR) of cTnI (post) , hs-CRP (post) , (cTnI+hs-CRP) (post) , C (cTnI) , C (hs-CRP) and C (cTnI+hs-CRP) were significantly lower in the effective group compared with those in the ineffective group (P<0.01). It was indicated that hs-CRP (post) and C (hs-CRP) , as well as the PR-cTnI (post) and the PR-C (cTnI) , may be used as independent factors for early therapeutic efficacy evaluation (P<0.05). In addition, the area under the ROC curve, as well as the associated sensitivity and specificity analysis for cTnI (post) , hs-CRP (post) , C (cTnI or hs-CRP) and Cr (cTnI or hs-CRP) , all indicated that these parameters were able to distinguish between the effective and the ineffective groups. The present study revealed that compared with the cTnI (post) and hs-CRP (post) , the C and the Cr of cTnI and hs-CRP may have enhanced value for evaluating the early therapeutic efficacy of AMI treatment.

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“…Caregiving could be treated as an external demand and might be appraised as dangerous or challenging, what could be important in terms of psychometric evaluations. 20,26…”

Section: Discussionmentioning

confidence: 99%

“…18,19 Interleukin-6 induces the production of C-reactive protein (CRP) in the liver, and a high serum CRP concentration is a risk factor for many diseases, including cardiovascular diseases and type 2 diabetes. 20 Therefore, this immune dysregulation could be the mechanism behind the physical health risks associated with caregiving. 18,19…”

mentioning

confidence: 99%

Depression But Not Inflammatory Markers Are Increased in Family Versus Nonfamily Caregivers of Persons With Dementia

Sadowska

Wyczalkowska-Tomasik

Zegarow

et al. 2020

J Geriatr Psychiatry Neurol

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We investigated quality of life (WHOQoL-BREF), perceived stress (PSS-10), anxiety and depression (HADS-M), life satisfaction (SWLS), and serum levels of interleukin-6 (IL-6), C-reactive protein (CRP), and cortisol in family caregivers (n = 94) and professional caregivers (n = 48) of demented patients, as well as among noncaregivers (n = 30). Compared with professional caregivers, family caregivers had higher scores in HADS-M depression ( P = .003) and anxiety ( P = .033), lower life satisfaction ( P = .04), and lower quality of life in psychological ( P = .02) and social relationship ( P = .03) domains. There were no differences in serum levels of IL-6, CRP, or cortisol between caregivers and control participants. In multivariable analysis, when family relationship was considered together with the time period of caregiving and results of the Mini-Mental State Examination test in care recipients (n = 118, 12.49 ± 7.99), only family relationship influenced scores in HADS-M depression ( P = .004), SWLS scores ( P = .011), and WHOQoL-BREF scores in psychological ( P = .011) and social relationship ( P = .008) domains. In conclusion, family caregivers are more stressed and have deeper depressive and anxiety disorders, lower life satisfaction, and lower quality of life than professional caregivers.

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Diagnostic value of carotid artery ultrasound and hypersensitive C-reactive protein in Type 2 diabetes mellitus patients with acute myocardial infarction in Chinese population

Cited by 4 publications

References 20 publications

Estimation of HsCRP and Cardiac Troponin I in Ischemic Heart Disease Iraqi Patients

Estimation of HsCRP and Cardiac Troponin I in Ischemic Heart Disease Iraqi Patients

Changes of cardiac troponin I and hypersensitive C‑reactive protein prior to and after treatment for evaluating the early therapeutic efficacy of acute myocardial infarction treatment

Depression But Not Inflammatory Markers Are Increased in Family Versus Nonfamily Caregivers of Persons With Dementia

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