Diagnostic Testing for Migraine and Other Primary Headaches

Evans, Randolph W.

doi:10.1016/j.ncl.2019.08.001

Cited by 19 publications

(6 citation statements)

References 62 publications

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“…These innate illnesses are brought on by nature and rely on kala (time). Examples of natural diseases are thirst, hunger, old age, mortality, and similar conditions [14,15] .No one can escape these diseases, but they can be changed. A person can avoid ageing and death if they can successfully overcome the constraints of time via the practise of yoga and samadhi.…”

Section: Discussionmentioning

confidence: 99%

Integrative Understanding of Geriatrics Through Ayurveda: A Review

Dravyekar,

Gulhane,

Mahulkar

2024

SDNJAY

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Section: Discussionmentioning

confidence: 99%

Integrative Understanding of Geriatrics Through Ayurveda: A Review

Dravyekar,

Gulhane,

Mahulkar

2024

SDNJAY

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“…The diagnosis of migraine is clinical and can be most often achieved by analysis of a patient's history and physical examination. 48 Clinical diagnostic criteria for migraine with and without aura are summarized in Table 2. Testing outside of the scope of history and physical such as blood work, neuroimaging, lumbar puncture, or electroencephalography are not typically required for the diagnosis of migraine.…”

Section: Diagnosismentioning

confidence: 99%

“…However, these additional diagnostic tests may be required to distinguish between migraine as a primary headache or a secondary headache with migraine-like presentation or when the diagnosis unclear. 48 The clinical diagnosis of migraine is important for the proper management of this disorder. A study by Diamond et al showed that of all the participants with migraine, 56.2% had ever had an established medical diagnosis of migraine.…”

Section: Diagnosismentioning

confidence: 99%

A Comprehensive Review of Zavegepant as Abortive Treatment for Migraine

Noor

Angelette

Lawson

et al. 2022

Health Psychology Research

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Migraine headache is a widespread and complex neurobiological disorder that is characterized by unilateral headaches that are often accompanied by photophobia and phonophobia. Migraine is one of the leading chief complaints in the emergency department with negative impacts on quality of life and activities of daily living. The high number of emergency presentations also results in a significant economic burden. Its risk factors include family history, genetics, sex, race, socioeconomics, the existence of comorbid conditions, and level of education. Triggers include stress, light, noise, menstruation, weather, changes in sleep pattern, hunger, dehydration, dietary factors, odors, and alcohol. The International Headache Society has defined criteria for the diagnosis of migraine with and without aura. The pathophysiology of migraine headaches is multifactorial so there are a variety of treatment approaches. The current treatment approach includes abortive medications and prophylactic medications. Abortive medications include the first-line treatment of triptans, followed by ergot alkaloids, and calcitonin gene-related peptide (CGRP) receptor antagonists along with supplemental caffeine and antiemetics. Trigeminal afferents from the trigeminal ganglion innervate most cranial tissues and many areas of the head and face. These trigeminal afferents express certain biomarkers such as calcitonin gene-related peptide (CGRP), substance P, neurokinin A, and pituitary adenylate cyclase-activating polypeptide that are important to the pain and sensory aspect of migraines. In this comprehensive review, we discuss Zavegepant, a calcitonin gene-related peptide receptor antagonist, as a new abortive medication for migraine headaches.

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“…The development of small-scale and reliable point-of-care testing (POCT) has allowed for analyses in multiple clinical contexts [14]. In this sense, different biomarkers, for which POCT are already available, have shown their association with headache, for instance the evaluation of serum urea nitrogen and creatinine is necessary to rule out renal-failure-associated headache; hypercalcemia, hyponatremia, hypoglycemia, and dehydration have been also associated with headache [15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Blood Biomarkers for Assessing Headaches in Healthcare Workers after Wearing Biological Personal Protective Equipment in a COVID-19 Field Hospital

Martin-Rodríguez

López-Izquierdo

Rubiales

et al. 2021

JPM

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The coronavirus disease 2019 (COVID-19) has led to a pandemic, which among other things, has highlighted biosafety as a key cornerstone in the management of disease transmission. The aim of this work was to analyze the role played by different blood biomarkers in predicting the appearance of headaches in healthcare workers wearing personal protective equipment (PPE) in a COVID-19 treatment unit. A prospective cohort study of 38 healthcare workers was performed during April 2020. Blood analysis, performed just before the start of a 4 hour shift, was carried out on all volunteers equipped with PPE. At the end of their shifts and after decontamination, they were asked if they had suffered from headache in order to obtain a binary outcome. The baseline creatinine value reflected a specific odds ratio of 241.36 (95% CI: 2.50–23,295.43; p = 0.019) and an area under the curve (AUC) value of 0.737 (95%CI: 0.57–0.90; p < 0.01). Blood creatinine is a good candidate for predicting the appearance of a de novo headache in healthcare workers after wearing PPE for four hours in a COVID-19 unit.

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Diagnostic Testing for Migraine and Other Primary Headaches

Cited by 19 publications

References 62 publications

Integrative Understanding of Geriatrics Through Ayurveda: A Review

Integrative Understanding of Geriatrics Through Ayurveda: A Review

A Comprehensive Review of Zavegepant as Abortive Treatment for Migraine

Blood Biomarkers for Assessing Headaches in Healthcare Workers after Wearing Biological Personal Protective Equipment in a COVID-19 Field Hospital

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