Diagnostic Procedures, Revascularization, and Inpatient Mortality After Acute Myocardial Infarction in Patients With Schizophrenia and Bipolar Disorder

Wu, Shu‐I; Chen, Su-Chiu; Juang, Jyh-Ming Jimmy; Fang, Chun-Kai; Liu, Shen‐Ing; Sun, Fang‐Ju; Kao, Kai-Liang; Dewey, Michael; Prince, Martin; Stewart, Robert

doi:10.1097/psy.0b013e31827612a6

Cited by 45 publications

(56 citation statements)

References 37 publications

(40 reference statements)

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“…According to our hypothesis, the lower rate of PSA tests could suggest that this negative association may reflect more an issue of method than an issue of substance. Since service-based disparities were noted repeatedly in the literature [9][10][11] , as well as in our data (Gal et al, submitted), it is possible that the lower rate of PSA tests among service users diagnosed with schizophrenia result in less biopsies, and the consequent lower rate of cancer diagnosis. This interpretation should be carefully weighted given the relatively lower rate of performance of PSA test preceding the cancer diagnosis.…”

Section: Discussionmentioning

confidence: 84%

“…Limited heterosexual activity with a subsequent decreased risk of sexual-transmitted infections. However, a methodological hypothesis cannot be excluded: given the disparities in the health care of persons with schizophrenia [9][10][11] , if service-users with schizophrenia are less often screened with prostate-specific antigen (PSA) tests compared to schizophrenia-free men the identification of prostate cancer may fall. We had the rare opportunity to explore the latter hypothesis in a study of medical services provided to persons with schizophrenia in a country with a national health insurance.…”

Section: Introductionmentioning

confidence: 99%

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Lower risk of prostate cancer in schizophrenia: fact or artifact?

2014

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-Background and Objectives: Reduced risk for prostate cancer in persons diagnosed with schizophrenia has been reported repeatedly. While genetic factors and antipsychotic medications were imputed, a methodological hypothesis could be raised: given the reported disparities of health services with regard to service users with schizophrenia these persons may be screened less often compared to schizophrenia-free counterparts resulting in undetected prostate tumors. The study objective was to compare the rates of performance of the prostate specific antigen (PSA) screening test among persons diagnosed with schizophrenia to matched-comparison subjects.Methods: A prospective historical epidemiological study which included service users with and without a diagnosis of schizophrenia (N = 52,131). Linkage was conducted between databases of the nation-wide psychiatric register and Israel's largest health maintenance organization. Annual performance of PSA tests was recorded between the years 2002-2009.Results: Service users with schizophrenia performed the PSA test 23% less than the comparison subjects. However, among service users who were diagnosed with prostate cancer only 44% performed the PSA test during the year prior to diagnosis.Conclusions: In line with our hypothesis, lower rates of PSA screening tests were conducted among service users with schizophrenia. However, the relatively low rate of this test prior to prostate cancer diagnosis ought to be noted.

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Section: Discussionmentioning

confidence: 84%

Section: Introductionmentioning

confidence: 99%

Lower risk of prostate cancer in schizophrenia: fact or artifact?

2014

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“…; Wu et al . ), while four studies found no significant difference in mortality after adjusting for demographic and medical factors (Bot et al . ; Buller et al .…”

Section: Resultsmentioning

confidence: 99%

“…; Wu et al . ). The use of hospital databases provided for standardized definitions across studies (ICD‐9‐CM coding) reduces bias in sample selection across the studies.…”

Section: Resultsmentioning

confidence: 99%

Safety of service users with severe mental illness receiving inpatient care on medical and surgical wards: A systematic review

Reeves

Henshall

Hutchinson

et al. 2018

Int J Mental Health Nurs

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This review aimed to synthesize the evidence on the likelihood of harm and mortality on medical and surgical inpatient wards for people with severe mental illness (SMI). From 937 results identified through database searching, and a further 10 papers identified through citation searching and hand searching, 11 papers met the criteria for inclusion in the final review. This review did not find strong evidence for higher in-hospital mortality in people with SMI. There was evidence that adverse events are higher in people with SMI. A higher likelihood of emergency instead of planned care, and poorer access to treatment were identified as potential contributing factors to these adverse events. In addition, service users with SMI were more likely to have a longer length of stay, associated with a higher cost of care. The severity of the mental illness increased the likelihood of harm or death, and people with schizophrenia were more likely than people with other mental illnesses to experience these adverse outcomes. There is evidence that people with SMI are provided with lower-quality health care, whereas higher-quality, better-planned care is required to overcome the inequalities in access faced by this vulnerable population.

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“…For more than a generation, the field of psychosomatic medicine has described the strong adverse impact of psychiatric illnesses on the course and outcome of a wide range of comorbid medical diseases, including cancer, cardiovascular disease, diabetes, and HIV/AIDS (1)(2)(3)(4). These relationships stubbornly persist in the absence of effective evidence-based strategies for disrupting the interplay between psychiatric and nonpsychiatric illness.…”

mentioning

confidence: 96%

Disrupting the Adverse Interplay Between Psychiatric and Medical Illnesses

Golden

2016

Psychosomatic Medicine

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Psychiatric illnesses increase the morbidity and mortality of comorbid medical disease, and current research targets the identification of specific mechanisms that account for this association. Psychotic illness complicates the management of chronic diseases where self-care activities often play a major role, such as in the regulation of blood glucose levels in diabetes. In this issue, Wykes et al. describe an interactive relationship between cognitive functioning and negative symptoms, self-efficacy, and diabetic control in patients with psychotic illnesses and Type 1 diabetes. Although high self-efficacy was associated with better hemoglobin A1C levels in patients with mild negative symptoms and higher cognitive function, in patients with more severe negative symptoms and lower cognitive function, high-self-efficacy was linked to higher A1C levels. These findings point to the need for designing diabetes management plans based on careful assessments of specific psychiatric symptomatology in this population. Severe mental illness is also associated with poor general physical health and higher rates of somatic complaints. Madan and colleagues describe in this issue an integrated model of psychiatric and medical care that substantially reduced physical symptoms in patients with severe mental illness during an 8-week hospitalization, with striking improvements in those presenting with substance abuse and sleep disorders. If these findings are shown to persist after discharge, then accountable care organizations should be encouraged to incorporate this more aggressive approach to caring for this vulnerable population. Such targeted approaches are likely to result in decreased utilization of outpatient medical services and improved long-term outcomes.

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Diagnostic Procedures, Revascularization, and Inpatient Mortality After Acute Myocardial Infarction in Patients With Schizophrenia and Bipolar Disorder

Cited by 45 publications

References 37 publications

Lower risk of prostate cancer in schizophrenia: fact or artifact?

Lower risk of prostate cancer in schizophrenia: fact or artifact?

Safety of service users with severe mental illness receiving inpatient care on medical and surgical wards: A systematic review

Disrupting the Adverse Interplay Between Psychiatric and Medical Illnesses

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