Diagnostic implications for myocardial ischemia of the circadian variation of the onset of chest pain

Does a circadian variation occur in myocardial ischemia over 48 hours in patients with unstable angina?

“…On the contrary, they noted an even a higher incidence of ischemia from 6:00 pm to midnight. Finally, it is worth noting the experience of Beamer et al 11 . These authors studied 3990 individuals with a history of chest pain admitted to the Emergency Department of seven different hospitals.…”

“…Reports exist indicating that ischemia, with or without symptoms, has a circadian variation in either stable 8,9 or unstable angina [10][11][12][13] . Moreover, we know neither the incidence of silent ischemia in individuals with unstable angina nor its variation throughout the 24 hours of a day in our patient population.…”

Circadian variation of acute st segment elevation myocardial infarction by anatomic location in a Turkish cohort

“…Studies on the circadian rhythm of AMI onset have suggested that the morning peak of incidence is related to other known daily rhythms [2,5,15]. One obvious explanation is the increase in physical and mental stress that occurs after waking.…”

Making a Case for Programmable Pumps Over Fixed Rate Pumps for the Management of Fluctuations in Chronic Pain and Spasticity: A Literature Review

“…Predictable pain patterns have been identified for many chronic conditions, including angina pectoris (46–50), asthma (51), migraine headaches (52), fibromyalgia (53), spinal cord injury (54), rheumatoid arthritis (55–57), and osteoarthritis (58). Folkard et al (59) studied diurnal variation in pain of 41 patients with various types of chronic pain, including: postherpetic neuralgia ( n = 8), low back pain ( n = 8), cancer pain ( n = 5), and other pain types (e.g., phantom‐limb pain, atypical facial neuralgia, etc.…”