Diagnostic Imaging Modalities to Assess Treatment Response of Bone Metastasis in Patients Receiving Palliative Radiotherapy: A Scoping Review of the Literature

Bala, Wasif; Chiu, Nicholas; Tao, Mary Jiayi; Lam, Henry; Chow, Edward; Probyn, Linda

doi:10.1177/0846537119888388

Cited by 4 publications

(3 citation statements)

References 35 publications

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Section: Introductionmentioning

confidence: 99%

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[Retracted] Value of CT Radiomics and Clinical Features in Predicting Bone Metastases in Patients with NSCLC

Chen

et al. 2022

Contrast Media & Molecular Imaging

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Objective. To explore the CT radiomic features and clinical imaging features of the primary tumor in patients with nonsmall cell lung cancer (NSCLC) before treatment and their predictive value for the occurrence of bone metastases. Methods. From June 2017 to June 2021, 195 patients with NSCLC who were pathologically diagnosed without any treatment in the Cancer Hospital Affiliated to Hainan Medical College were retrospectively analyzed, and they were divided into a bone metastasis group and a nonbone metastasis group. The relationship between clinical imaging features and bone metastasis in patients was analyzed by the t-test, rank sum test, and χ2 test. At the same time, ITK software was used to extract the radiomic characteristics of the primary tumor of the patients, and the patients were randomly divided into a training group and a validation group in a ratio of 7 : 3. The training model was validated in the validation group, and the performance of the model for predicting bone metastases in NSCLC patients was verified by the ROC curve, and a multivariate logistic regression prediction model was established based on the omics parameters extracted from the best prediction model combined with clinical image features. Results. Seven features were screened from the primary tumor by LASSO to establish a model for predicting metastasis. The area under the curve was 0.82 and 0.73 in the training and validation sets. The best omics signature and univariate analysis suggested clinical imaging factors P < 0.05 associated with bone metastases were included in multivariate binary logistic analysis to obtain clinical characteristics of the primary tumor such as gender (OR = 0.141, 95% CI: 0.022–0.919, P = 0.04), increased Cyfra21-1 (OR = 0.12, 95% CI: 0.018–0.782, P = 0.027), Fe content in blood (OR = 0.774, 95% CI: 0.626–0.958, P = 0.018), CT signs such as lesion homogeneity (OR = 0.052, 95% CI: 0.006–0.419, P = 0.006), pleural indentation sign (OR = 0.007, 95% CI: 0.001–0.696, P = 0.034), and omics characteristics glszm_Small Area High Gray Level Emphasis (OR = 0.016, 95% CI: 0.001–0.286, P = 0.005) were independent risk factors for bone metastasis in patients. Conclusion. The prediction model established based on radiomics and clinical imaging features has high predictive performance for the occurrence of bone metastasis in NSCLC patients.

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Section: Introductionmentioning

confidence: 99%

“…For patients with bone metastases, the current treatment standard includes palliative radiotherapy such as external beam radiotherapy. However, the local control rate of patients is low [ 4 – 6 ]. Therefore, exploring new treatment methods for bone metastasis is of great significance to improving the quality of life of patients.…”

Section: Introductionmentioning

confidence: 99%

[Retracted] Value of CT Radiomics and Clinical Features in Predicting Bone Metastases in Patients with NSCLC

Chen

et al. 2022

Contrast Media & Molecular Imaging

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“…Hospital health professionals are expected to play an optimal role in providing good healing (Kaasa et al, 2018). Treatment of bone cancer in medical care includes surgical amputation, chemotherapy, or radiotherapy using high-energy radiation (Bala et al, 2020;Ministry of Health Republic of Indonesia, 2018). Bone cancer patients experience various complaints that cause a decrease in well-being.…”

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confidence: 99%

Physical Well-Being Needs of Bone Cancer Patients during Treatment in the Hospital: A Qualitative Study

Priyanto,

Fauzi Kamal,

Dahlia

et al. 2023

Nurs. Med. J. Nursing

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Background: Bone cancer patients undergoing hospitalization require support to manage physical challenges for optimal healing and recovery. The physical aspects experienced by the patients significantly affect their physical well-being. Addressing these aspects is essential for nurses in providing care. However, comprehensive assessments of bone cancer patients’ physical needs have not been thoroughly explored. Purpose: This study aimed to explore the physical well-being needs of patients with bone cancer undergoing hospitalization. Methods: This qualitative study with a phenomenological approach was conducted among 14 bone cancer patients selected through purposive sampling. The criteria included patients with a primary cancer diagnosis, undergoing hospitalization at a cancer center, and having good orientation and verbal communication abilities. In-depth interviews were employed to delve into the patients’ well-being needs. To triangulate the data, 12 cancer nurses were involved. Data analysis utilized the Creswell method.Results: This study found chronic pain and bone lumps as fundamental physical challenges, leading to disruptions in physical movement, sleep disturbances, and dependency on others for self-care. Six themes emerged regarding the physical well-being needs of hospitalized bone cancer patients: goals and needs for physical well-being, need for pain management, need for physical mobility, need for sleep and rest, need for self-care, and the meaning of physical well-being for patients. Physical well-being provides a significant meaning in achieving nursing goals.Conclusion: This study shows the significance of addressing pain management, physical mobility, sleep and rest, and self-care for the physical well-being of bone cancer patients. Nurses should be able to identify various physical complaints and help improve the physical well-being of bone cancer patients.

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Radiation Therapy for Painful Bone Metastases: Fractionation, Recalcification, and Symptom Control

Tseng

2023

Seminars in Radiation Oncology

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Diagnostic Imaging Modalities to Assess Treatment Response of Bone Metastasis in Patients Receiving Palliative Radiotherapy: A Scoping Review of the Literature

Cited by 4 publications

References 35 publications

[Retracted] Value of CT Radiomics and Clinical Features in Predicting Bone Metastases in Patients with NSCLC

[Retracted] Value of CT Radiomics and Clinical Features in Predicting Bone Metastases in Patients with NSCLC

Physical Well-Being Needs of Bone Cancer Patients during Treatment in the Hospital: A Qualitative Study

Radiation Therapy for Painful Bone Metastases: Fractionation, Recalcification, and Symptom Control

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