Diagnostic imaging in the study of human hepatobiliary fascioliasis

Cantisani, Vito; Cantisani, Carmen; Mortelé, Koenraad J.; Pagliara, E.; D’Onofrio, Mirko; Fernández, Manuel; D’Ambrosio, U.; Lombardi, V.; Marigliano, Chiara; Ricci, Paolo

doi:10.1007/s11547-009-0454-y

Cited by 12 publications

(12 citation statements)

References 18 publications

(39 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Plasma levels of IgG directed against F. hepatica increase in two weeks after infection. [6] Indirect immunological techniques have an advantage of being applicable during all stages of the disease, and have also recently proved to be useful for monitoring post-treatment evolution. Enzyme-linked immunosorbent assay (ELISA) is a biochemical technique mainly used to detect the presence of antifluke antibodies in the serum.…”

Section: Diagnosismentioning

confidence: 99%

See 1 more Smart Citation

Radiological Imaging Features of Fasciola hepatica Infection – A Pictorial Review

Duşak

Onur

Çiçek

et al. 2012

Journal of Clinical Imaging Science

View full text Add to dashboard Cite

Fascioliasis refers to a zoonosis caused by Fasciola hepatica, a trematode infecting herbivores, but also occurs in humans who ingest the metacercaria found in fresh water plants. Infection in humans is common in developing countries and is also not uncommon in Europe. Diagnosis of this infection is difficult, as the history and symptoms are nonspecific and stool analysis for eggs is negative until the disease is in an advanced state by when the parasite has reached the biliary system. The clinical course consists of two phases; first a hepatic parenchymal phase in which immature larvae invade the liver parenchyma, followed by a ductal phase characterized by the excretion of larvae into the bile ducts. Parenchymal Phase: Ultrasonography (US) findings are nonspecific in this early phase. Computerized tomography (CT) may demonstrate subcapsular low attenuation regions in the liver. Magnetic Resonance imaging (MRI) can also be utilized to establish liver parenchymal involvement, and is better than CT in characterizing hemorrhagic lesions, as well as identifying more lesions relative to CT. Ductal Phase: US examination is most useful at this stage, with its ability to demonstrate the live movement of the worms within the dilated ducts. A CT demonstrates dilated central biliary ducts with periportal tracking, whereas, mild ductal dilatation is poorly appreciated under MRI. Therefore, familiarity with the multimodality imaging features of fascioliasis, in combination with an available confirmatory enzyme-linked immunoassay, would be most helpful for early diagnosis.

show abstract

Section: Diagnosismentioning

confidence: 99%

“…Intermediate signal-filling defects representing worms can be seen in the dilated ducts on the MRI [Figure 14]. [6]…”

Section: Diagnosismentioning

confidence: 99%

Radiological Imaging Features of Fasciola hepatica Infection – A Pictorial Review

Duşak

Onur

Çiçek

et al. 2012

Journal of Clinical Imaging Science

View full text Add to dashboard Cite

show abstract

“…Kontrastlı USG hepatik fasioliaziste tanı ve takipte daha yararlı olabilir (23). BT'de subkapsüler, prebiliyer veya periportal lineer veya dallanma gösteren, mikroabselere benzer hipodens nodüller görülür (6,24), MRG karaciğer parankimal tutulumu ve hemorajik lezyonları BT'den daha iyi gösterir. Biliyer fazda safra yollarındaki dilatasyonu göstermede USG ve MR kolanjiyografi daha kullanışlıdır.…”

Section: Discussionunclassified

Hepatik kitle ile prezente olan, ERCP ile ekstraksiyonu yapılan Fasciola hepatica: olgu sunumu ve literatürün gözden geçirilmesi

Uyanıkoğlu¹,

Demır²,

Akyüz³

et al. 2015

Endoskopi Gastrointestinal

View full text Add to dashboard Cite

Presentation with hepatic mass and ERCP extraction of Fasciola hepatica: A case report and review of the literature Fasciola hepatica infeksiyonu ülkemizin bazı bölgelerinde endemik olarak rastlanan bir karaciğer trematodudur. Klinik bulgular nonspesifik olup; karın ağrısı, sağ üst kadranda hassasiyet şeklinde olabilir. Laboratuvarda eozinofili, karaciğer enzimlerinin yükselmesi, pozitif seroloji görülür. Görüntüleme yöntemlerinde karaciğerde çok sayıda nodüller ve safra yollarında dilatasyon görülür. Triclabendazol hepatik ve biliyer fazda etkilidir. Endoskopik retrograd kolanjiopankreatografi ile canlı Fasciola hepaticaların biliyer kanaldan uzaklaştırılması ile de tedavi edilir. Burada karaciğerde kitle nedeniyle tetkik edilen, safra yollarında dilatasyona neden olan ve endoskopik retrograd kolanjiopankreatografi ile tedavi edilen fasciola hepaticalı genç bayan olgusu sunulmuştur. Anahtar kelimeler: Fasciola hepatica, eozinofiliFasciola hepatica is a liver trematode that is endemic in some parts of Turkey. Clinical findings are nonspecific, such as abdominal pain and right upper quadrant tenderness. Eosinophilia, elevated liver enzymes and positive serology can be detected in laboratory investigations, while multiple nodules in the liver and dilated bile ducts can be seen in imaging modalities. Triclabendazole is effective in the hepatic and biliary phases. Fasciola hepatica is also treated with endoscopic retrograde cholangiopancreatography by biliary duct removal. Herein, we present a young woman who was evaluated with a mass in the liver and biliary tract dilatation caused by Fasciola hepatica and who was treated with endoscopic retrograde cholangiopancreatography.

show abstract

“…The ductal phase can show dilatation of bile ducts with wall thickening and sometimes tortuous shape. Solid contents in the ductal lumina or inside the gallbladder can correspond to debris or the flukes themselves [7, 100–102]. …”

Section: Fascioliasismentioning

confidence: 99%

“…Biliary ducts dilatation is better depicted on cholangiographic sequences. Sometimes adult worms can be seen as low-signal-filling defects inside the central or extrahepatic bile ducts [7, 100, 104]. …”

Section: Fascioliasismentioning

confidence: 99%

Unexpected hosts: imaging parasitic diseases

et al. 2016

View full text Add to dashboard Cite

Radiologists seldom encounter parasitic diseases in their daily practice in most of Europe, although the incidence of these diseases is increasing due to migration and tourism from/to endemic areas. Moreover, some parasitic diseases are still endemic in certain European regions, and immunocompromised individuals also pose a higher risk of developing these conditions. This article reviews and summarises the imaging findings of some of the most important and frequent human parasitic diseases, including information about the parasite’s life cycle, pathophysiology, clinical findings, diagnosis, and treatment. We include malaria, amoebiasis, toxoplasmosis, trypanosomiasis, leishmaniasis, echinococcosis, cysticercosis, clonorchiasis, schistosomiasis, fascioliasis, ascariasis, anisakiasis, dracunculiasis, and strongyloidiasis. The aim of this review is to help radiologists when dealing with these diseases or in cases where they are suspected. Teaching Points • Incidence of parasitic diseases is increasing due to migratory movements and travelling. • Some parasitic diseases are still endemic in certain regions in Europe. • Parasitic diseases can have complex life cycles often involving different hosts. • Prompt diagnosis and treatment is essential for patient management in parasitic diseases. • Radiologists should be able to recognise and suspect the most relevant parasitic diseases.

show abstract

Diagnostic imaging in the study of human hepatobiliary fascioliasis

Cited by 12 publications

References 18 publications

Radiological Imaging Features of Fasciola hepatica Infection – A Pictorial Review

Radiological Imaging Features of Fasciola hepatica Infection – A Pictorial Review

Hepatik kitle ile prezente olan, ERCP ile ekstraksiyonu yapılan Fasciola hepatica: olgu sunumu ve literatürün gözden geçirilmesi

Unexpected hosts: imaging parasitic diseases

Contact Info

Product

Resources

About