Diagnostic imaging findings of pelvic retroperitoneal ganglioneuroma in a child: a case report with the emphasis on initial ultrasound findings

Dt, Mut; Up, Orhan Soylemez; Demir, Mustafa Kemal; Tanık, Canan; Özer, Ali Fahir

doi:10.11152/mu.2013.2066.181.usf

Cited by 4 publications

(2 citation statements)

References 14 publications

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“…Ultrasound normally reveals a homogeneous or slightly heterogeneous, hypoechoic, solid, and hypovascular mass (25), but our studies suggested 50% of the masses exhibited varied blood flow signals. On plain CT, previous studies revealed that the densities varied from 15 to 38 HU with a mean of around 30 HU, and fine and punctate calcifications can be seen in some cases instead of amorphous and coarse ones seen in neuroblastomas (24)(25)(26). Late-phase enhancement in a range of 10-20 HU has been reported for GNs (27).…”

Section: Discussionmentioning

confidence: 60%

Primary Retroperitoneal Ganglioneuroma: A Retrospective Cohort Study of 32 Patients

Xiao

Zhao

et al. 2021

Front. Surg.

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Purpose: To investigate the clinical characteristics, diagnosis, differential diagnosis, therapy options, and outcomes of retroperitoneal ganglioneuroma.Methods: In this retrospective study, we collected and analyzed the clinical data of 32 patients diagnosed with retroperitoneal ganglioneuroma and admitted to Peking Union Medical College Hospital from October 2012 to August 2019.Results: Among our 32 cases with retroperitoneal ganglioneuroma, the male-to-female ratio was 1:3 and the mean age was 35. Only 25% of the cases presented with abdominal pain while more than 65% had no specific symptoms. The masses could be found through physical examination in only five patients. Most of the tumors are located near the renal area. They were usually single and displayed an embedded growth pattern with diameters <10 cm, clear borders, and soft texture. For radiological imaging, the majority of tumors demonstrated soft tissue density with mild-to-moderate enhancement on CT imaging and showed hypoecho with moderate blood flow signals in ultrasound. No significantly abnormal laboratory examinations were found in most patients. Of all the 32 patients, 2 chose surveillance after biopsy due to difficulties in operation, while others chose surgical resection. The mean follow-up time was 15.8 months among 26 patients. The tumor remained stable in the surveillance cases. Residual tumors were found in four cases receiving operations with no progress and discomfort. No recurrence was seen in all patients.Conclusions: The retroperitoneal ganglioneuroma is a benign tumor without specific clinical manifestations or significant laboratory findings. Typically, it is shown as low density with a clear border and an embedded growth pattern in radiological imaging. The overall prognosis is good. Surgery is an effective approach with possible severe complications. Incomplete resection or surveillance can be considered for some cases where complete resection is difficult to achieve.

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Section: Discussionmentioning

confidence: 60%

Primary Retroperitoneal Ganglioneuroma: A Retrospective Cohort Study of 32 Patients

Xiao

Zhao

et al. 2021

Front. Surg.

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“…Extra-adrenal retroperitoneal ganglioneuromas in pediatric population are very rare. Our literature survey (PubMed/MEDLINE, Scopus, and Web of Science) revealed a few reported cases and small case series (1,4,7,(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20) with very few cases reported in the patients <10 years (summarized in Table 1). Scherer et al (2001) reported the largest case series of 5 patients (4 patients under the age of 10) depicting the radiological (CT and MRI) features of retroperitoneal GNs.…”

Section: Fig 3a-b Hematoxylin and Eosin (Hande) Slides Of The Moderately Cellular Neoplasm At Low Power (40´) Magnification (A); The Tumomentioning

confidence: 98%

A Case of Extra-adrenal Retroperitoneal Ganglioneuroma in a 9-year-old Female: A New Case Report with a Comprehensive Literature Review

et al. 2020

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Objective -We present herein a new case and survey comprehensively literature on this rare condition. Case report -A 9-yearold girl with a medical history of surgical correction of clubfoot three months earlier presented to our department with an incidentally detected abdominal mass during diagnostic workup for orthopedic surgery. A CT scan revealed a solid right extra-adrenal mass measuring 7×6 cm. It was compressing/involving the infrahepatic part of inferior vena cava, right renal vein and artery with an incomplete encasing of the abdominal aorta. The surgery was successfully performed. The histopathological analysis confirmed GN. Conclusions -Although pediatric extra-adrenal retroperitoneal ganglioneuroma (GN) are rare, their propensity for enveloping major blood vessels is not. GNs should be considered in the differential diagnosis of any circumscribed retroperitoneal mass. These tumors can be successfully treated with surgery that leads to an excellent outcome, even in case of incomplete resections with tumor residuals <2 cm.

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Myxopapillary Ependymoma and Rare Tumors

Bruckbauer

Hines

Perez

et al. 2020

Tumors of the Spinal Canal

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Diagnostic imaging findings of pelvic retroperitoneal ganglioneuroma in a child: a case report with the emphasis on initial ultrasound findings

Cited by 4 publications

References 14 publications

Primary Retroperitoneal Ganglioneuroma: A Retrospective Cohort Study of 32 Patients

Primary Retroperitoneal Ganglioneuroma: A Retrospective Cohort Study of 32 Patients

A Case of Extra-adrenal Retroperitoneal Ganglioneuroma in a 9-year-old Female: A New Case Report with a Comprehensive Literature Review

Myxopapillary Ependymoma and Rare Tumors

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