Diagnostic Evidence of Staphylococcus Warneri as a Possible Cause of Bovine Abortion

Abstract

Abstract. Following a routine necropsy of a bovine fetus aborted at 5 months of gestation, placenta, fetal tissue samples, and stomach contents were subjected to a number of laboratory tests. Staphylococcus warneri was isolated in pure culture from the lung, liver, and stomach contents, whereas the placenta yielded S. warneri and a number of contaminants. Gross evaluation of agar plates showed predominant colonies to be morphologically consistent with those of S. warneri and the identity of the agent was further confirmed on a Trek Diagnostic Systems Sensititre, gram-positive identification (GPID) plate. Microscopic evaluation of fetal tissue sections showed extensive necrotizing lesions of the tongue, lung, and placenta in which there were numerous coccoid shaped gram-positive bacteria with morphology consistent with Staphylococcus spp. These results provide strong diagnostic evidence of S. warneri as a possible cause of bovine abortion and suggest there should be further investigations into the abortivirulence of this agent.

Evaluation of Antibacterial Activity and Phenolic Contents of Four Nigerian Medicinal Plants

“…This pathogen was found as part of the skin flora on humans and animals and has been suggested as a cause of abortion in cattle and humans [27]. Furthermore, it has been also associated with urinary tract infection [28], meningitis [29], orthopedic infections [27], and endocarditis [30]. On the other hand, K. pneumonia, inhibited by ethanol extract of H. verticillaris in the present study, a pathogen, can cause inflammation and hemorrhagic in human lungs.…”

“…In the current study, S. warneri was found as the most sensitive pathogen to three tested plant extracts including H. verticillaris, I. tricantha and E. cyclocar pum. This pathogen was found as part of the skin flora on humans and animals and has been suggested as a cause of abortion in cattle and humans [27]. Furthermore, it has been also associated with urinary tract infection [28], meningitis [29], orthopedic infections [27], and endocarditis [30].…”

Whole genome sequence and comparative genome analyses of multi-resistant Staphylococcus warneri GD01 isolated from a diseased pig in China

“…Over the past three decades, clinical reports have pointed out that S. warneri is an opportunistic etiological agent frequently isolated from the immunocompromised cases bearing bacteremia, sepsis with multiple abscesses, orthopedic infections, vertebral osteomyelitis, and ventricular shunt infections [3][4][5][6][7]. S. warneri has been also suggested to be a culprit of bovine abortion, indicating it is a zoonotic pathogen [8].…”

Microbiome Profile in Adult Balanoposthitis Patients: Relationship with Redundant Prepuce, Skin Physical Barrier Status and Inflammation

“…Staphylococcus warneri is a coagulase-negative pathogen capable of producing several virulent factors, such that factors with ability to adhere and invade human epithelial cells, to form bio lm via ica-independent mechanisms, and to destroy cells by extracellular toxins [20]. Moreover, Staphylococcus warneri has been shown to be involved in spontaneous abortion in cattle [21] and humans [22]. Whether BP was associated with spontaneous abortion is an interesting topic to investigate.…”