Diagnostic Criteria for Atopic Dermatitis: A Systematic Review

Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three

“…These questions on symptoms of eczema include both sensitive and specific questions that are repeatable and have reasonable content, construct, concurrent, and predictive validity. 12,18,19 The key outcome reported (current symptoms of eczema) is that of respondents who answered positively to the question, ''Has your child/Have you had this itchy rash at any time in the past 12 months?'' and answered positively to the question, ''Has this itchy rash at any time affected any of the following places: the folds of the elbows, behind the knees, in front of the ankles, under the buttocks, or around the neck, ears or eyes?''…”

Neonatal total IgE and respiratory tract infections in children with intrauterine smoke exposure

“…However, within the PIAMA cohort, is has been shown that elevated neonatal tIgE (≥0.50 IU/ml) is associated with sensitisation at 1 year 22. Moreover, there is disagreement about the definition of atopic dermatitis, but compared with other definitions possible with the available data from the PIAMA study, the present definition seems a fairly good indicator of atopic dermatitis 31. Finally, response bias may have occurred if the association between ETS exposure and frequent RTI was different for the children who were included in the analyses and those who were excluded because of missing information, leading to an overestimation of the effect.…”

The relation between interleukin-31 serum levels and Staphylococcus aureus skin colonization in pediatric atopic dermatitis

“…The serum level of IL-31 as well as S. aureus skin colonization density were determined for patients before and after receiving treatment for their condition, as well as for controls. Both sets of criteria have been validated for their diagnostic sensitivity and specificity [4]. Results A significant association was found between IL-31 serum levels and AD (Po0.001), but it did not correlate with disease severity nor with pruritus intensity.…”