Diagnostic challenges in a rare case of müllerian adenofibroma of the uterus: instructive case and literature review

Skorupskaite, Karolina; Al‐Nafussi, Awatif; McKillop, Graham

doi:10.1016/j.mpdhp.2011.10.004

Cited by 2 publications

(3 citation statements)

References 20 publications

(32 reference statements)

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“…Hysterectomy assures complete excision, as well as permitting the thorough sampling needed to exclude the possibility of adenosarcoma. Indeed, most patients with adenofibroma underwent hysterectomy, with none showing tumor recurrence [ 1 – 14 , 16 – 18 ].…”

Section: Discussionmentioning

confidence: 99%

“…Only approximately 30 cases have been reported to date ( Table 1 ) [ 1 – 18 ]. Attempts have been made to diagnose these tumors using ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), hysteroscopy, and/or biopsy, but these methods were successful in correctly identifying adenofibroma in only three patients [ 3 , 16 , 17 ]. To date, only three patients each were assessed using MRI [ 11 , 12 , 14 ] and hysteroscopy [ 5 , 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

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Magnetic Resonance Imaging and Flexible Hysterofiberscopic Findings of a Uterine Adenofibroma: Case Report and Literature Review

Watanabe

Harada

Nobuhara

et al. 2018

Case Reports in Obstetrics and Gynecology

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To our knowledge, highly detailed findings of flexible hysterofiberscopy in patients with adenofibroma have not been described. A 75-year-old nulliparous asymptomatic woman presented with a uterine polyp, which exhibited punctate heterogeneous hyperintensity or islands of isointense-to-hypointense signals on T2-weighted magnetic resonance imaging (MRI), hypointense signals on T1-weighted images (T1WI), and a little enhancement on contrast-enhanced T1WI. Flexible hysterofiberscopy revealed a red-pink polyp with a white-yellow, cobblestone-like surface easily deformed by perfusion fluid. The tumor was diagnosed histologically as an adenofibroma. Total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed. The tumor in the uterus was necrotic macroscopically and histologically, and a residual adenofibroma could not be confirmed. At present, two years after surgery, the patient remains healthy. MRI and hysterofiberscopy can reveal the histological features of uterine adenofibromas and be useful for their diagnosis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Magnetic Resonance Imaging and Flexible Hysterofiberscopic Findings of a Uterine Adenofibroma: Case Report and Literature Review

Watanabe

Harada

Nobuhara

et al. 2018

Case Reports in Obstetrics and Gynecology

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show abstract

“…Conservative treatments such as curettage or polypectomy for Müllerian adenofibroma are not enough due to the probability of the recurrent nature of these tumors. Therefore, hysterectomy is the treatment of choice in cases with adenofibroma at post-menopausal age in order to complete excision and to obtain a sample to exclude adenosarcoma (10). Because this is a rare endometrial lesion, the probability that these lesions develop a malignant tumor, and their potential complication we present this case.…”

Section: Introductionmentioning

confidence: 99%

Endometrial adenofibroma, A Case Report

Moradan

Hosseinzadeh

2019

Middle East J Rehabil Health Stud

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Introduction: Adenofibroma is a type of mixed mesodermal tumor that both epithelial and stromal components are benign, and often originate from endometrium at postmenopausal age. Uterine adenofibroma is an extremely rare tumor and this lesion must be differentiated from some benign or malignant lesions of the uterus, particularly adenosarcoma. Because of the rarity and importance of such histopathology at post-menopausal age, this case is presented. Case Presentation: A 63-year-old woman, parity 9, who was at menopause period with a history of prolonged and severe no bloody vaginal discharge during the past 3 months was referred to our center. Transvaginal ultrasonography revealed a hyperechoic area with the dimensions 65 × 37 × 33 mm inside the endometrial cavity, that was suspicious to severe endometrial hyperplasia or malignancy. Tumor marker tests (BHCC, LDH, αFP, CA125, CA19-9, and CEA) were in normal limit. Endometrial biopsy by pipelle was unsatisfactory for diagnosis. Total abdominal hysterectomy was done, and the result of histopathology confirmed endometrial adenofibroma with the dimensions 70 × 47 × 40 mm. Conclusions: The presence of a hyperechoic area of the endometrium with complain of prolonged vaginal discharge in post menopause subjects could attribute to endometrial adenofibroma.

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Diagnostic challenges in a rare case of müllerian adenofibroma of the uterus: instructive case and literature review

Cited by 2 publications

References 20 publications

Magnetic Resonance Imaging and Flexible Hysterofiberscopic Findings of a Uterine Adenofibroma: Case Report and Literature Review

Magnetic Resonance Imaging and Flexible Hysterofiberscopic Findings of a Uterine Adenofibroma: Case Report and Literature Review

Endometrial adenofibroma, A Case Report

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