Diagnostic and therapeutic difficulties in the cutaneous form of Langerhans cell histiocytosis in infant
Hubert Arasiewicz,
Michał Dec,
Lilianna Lesniak-Jakubiec
Abstract:Introduction: Langerhans cell histiocytosis is an uncommon inflammatory and neoplastic condition of myeloid dendritic cells. Langerhans cell histiocytosis presents with a wide spectrum of clinical manifestations, ranging from single-system involvement to disseminated disease involving multiple organs. Diagnosis is based on a combination of clinical features, radiological findings, and histopathological examination. Positive immunohistochemical staining of lesional cells for CD1a and S100 is necessary for defin… Show more
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