Diagnostic and Therapeutic Delay of Rheumatoid Arthritis and its Relationship With Health Care Devices in Catalonia. The AUDIT Study

Corominas, H.; Narváez, Javier; Díaz-Torné, Cèsar; Salvador, Georgina; Gómez-Caballero, Maria Eugenia; Fuente, Diana de la; Campoy, Ester; Roig-Vilaseca, Daniel; Clavaguera, Teresa; Morlà, Rosa; Torrente-Segarra, Vicenç; Arasa, X.; Gómez-Puerta, José A.; Möller, Ingrid; Alegre, Cayetano; Graell, Eduard; Ponce, Andrés; Pérez-García, Carolina; Fíguls, Ramon; Sirvent, Elena; Poca, V.; Sanmartí, Raimón

doi:10.1016/j.reumae.2015.08.001

Cited by 12 publications

(19 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Results of the present study (20% reported PR more than 6 months prior to ERA and more than 40% within 1 year prior to diagnosis) are consistent with a previously reported rate of 23% and 50% but higher than two other studies (15% of 158 patients with RA had PR and 5% in another study ).…”

Section: Discussionsupporting

confidence: 92%

Palindromic Rheumatism Frequently Precedes Early Rheumatoid Arthritis: Results From an Incident Cohort

Ellingwood

Schieir

Valois

et al. 2019

ACR Open Rheumatology

View full text Add to dashboard Cite

BackgroundThis multicenter incident cohort aimed to characterize how often early rheumatoid arthritis (ERA) patients self‐report episodic joint inflammation (palindromic rheumatism) preceding ERA diagnosis and which characteristics differentiate these patients from those without prior episodic symptoms.MethodsData were from patients with early confirmed or suspected RA (more than 6 weeks and less than 12 months) enrolled in the Canadian Early ArThritis CoHort (CATCH) between April 2017 to March 2018 who completed study case report forms assessing joint pain and swelling prior to ERA diagnosis. Chi‐square and t tests were used to compare characteristics of patients with and without self‐reported episodic joint inflammation prior to ERA diagnosis. Multivariable logistic regression was used to identify sociodemographic and clinical measures associated with past episodic joint inflammation around the time of ERA diagnosis.ResultsA total of 154 ERA patients were included; 66% were female, and mean (SD) age and RA symptom duration were 54 (15) years and 141 (118) days. Sixty‐five (42%) ERA patients reported a history of episodic joint pain and swelling, half of whom reported that these symptoms preceded ERA diagnosis by over 6 months. ERA patients with past episodic joint inflammation were more often female, had higher income, were seropositive, had more comorbidities, fewer swollen joints, and lower Clinical Disease Activity Index (CDAI) around the time of ERA diagnosis (P < 0.05). These associations remained significant in multivariable regression adjusting for other sociodemographic and RA clinical measures.ConclusionAlmost half of ERA patients experienced episodic joint inflammation prior to ERA diagnosis. These patients were more often female, had higher income, and presented with milder disease activity at ERA diagnosis.

show abstract

Section: Discussionsupporting

confidence: 92%

Palindromic Rheumatism Frequently Precedes Early Rheumatoid Arthritis: Results From an Incident Cohort

Ellingwood

Schieir

Valois

et al. 2019

ACR Open Rheumatology

View full text Add to dashboard Cite

show abstract

“…Corominas et al 16 analyzed the diagnostic and therapeutic delay in RA and its relationship with health care departments in Catalunya. He found that the mean time from the onset of symptoms to the prescription of a disease-modifying drug in patients with RA was 11 months and that those patients who visited health care departments, such as clinics specializing in primary health care and arthritis, were treated sooner with disease-modifying drugs.…”

Section: Discussionmentioning

confidence: 99%

Clinical and serological characteristics of Ecuadorian patients with rheumatoid arthritis

Ríos¹,

Maldonado

Paredes

et al. 2017

OARRR

View full text Add to dashboard Cite

BackgroundRheumatoid arthritis (RA) is a systemic autoimmune inflammatory disease, wherein late diagnosis and treatment leads to deformities and disability.ObjectiveThe aim of the study was to assess and describe the clinical and immunological characteristics, activity status of the disease, and functional capacity in a cohort of Ecuadorian patients with RA.MethodsThis is a cross-sectional, descriptive study conducted on a population of patients with prediagnosed RA from public and private Ecuadorian rheumatology clinics. This study investigated 400 patients with a mean age of 50 years, 353 (82.25%) of which were female.ResultsThe study showed that 44.3%, 83.5%, 60.3%, 41.8%, 37.5%, and 11.5% had an acute onset of the disease, symmetrical polyarthritis, morning stiffness exceeding 1 h, dry eyes, dry mouth, and rheumatoid nodules, respectively. A total of 89.7% presented with positive rheumatoid factor, and 96.5% were anti-citrullinated protein antibody positive.ConclusionThis is the largest Ecuadorian cohort of patients with RA; clinical features are similar to those of other Latin American populations.

show abstract

“…In our study, the median time delay between symptom onset and rheumatologist evaluation was 28 months, in contrast with other authors who reported a median delay of 10 months. 3 Even though 82% of patients were treated at a rheumatology clinic before 12 weeks, the wait time between seeing a PCP and seeing a rheumatologist was 9.5 weeks on average. Although diagnostic concordance was low between physicians, we observed that the presence of pain in the upper limbs (including hands, elbows, and shoulders) and morning stiffness were associated with a final diagnosis of RA (odds ratio = 10.5, 95% confidence interval = 1.3-81.4; and odds ratio = 3.04, 95% confidence interval = 1.69-5.45, respectively).…”

Section: Letter To the Editormentioning

confidence: 99%

Time Delay to Rheumatology Consultation

Vega‐Morales¹,

Covarrubias-Castañeda²,

Arana-Guajardo³

et al. 2016

Am J Med Qual

View full text Add to dashboard Cite

Diagnostic and Therapeutic Delay of Rheumatoid Arthritis and its Relationship With Health Care Devices in Catalonia. The AUDIT Study

Cited by 12 publications

References 16 publications

Palindromic Rheumatism Frequently Precedes Early Rheumatoid Arthritis: Results From an Incident Cohort

Palindromic Rheumatism Frequently Precedes Early Rheumatoid Arthritis: Results From an Incident Cohort

Clinical and serological characteristics of Ecuadorian patients with rheumatoid arthritis

Time Delay to Rheumatology Consultation

Contact Info

Product

Resources

About