Diagnostic and clinical implications of pituicytoma

Furtado, Sunil V.; Ghosal, Nandita; Venkatesh, Prasanna K.; Gupta, Kanchan; Hegde, Alangar S.

doi:10.1016/j.jocn.2009.09.047

Cited by 39 publications

(25 citation statements)

References 16 publications

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“…The clinical details were not available in one case. The most common symptoms of pituicytoma were vision and visual field disorders (44 cases, 56.4%), headaches (34 cases, 43.6%), hypopituitarism (17 cases, 21.8%), hyposexuality (16 cases, 20.5%), sexual dysfunction (7 cases, 9.0%), menstrual disorder (7 cases, 9.0%), dizziness (6 cases, 7.7%), diabetes insipidus (3 cases, 3.8%) (10-12), epilepsy (3 cases, 3.8%) (13)(14)(15), gynecomastia (3 cases, 3.8%) (10,16,17) and spontaneous tumor hemorrhage (1 case, 1.3%) (18). There were also sporadic cases that presented with nausea (6), vomiting (9) or edema (9).…”

Section: Discussionmentioning

confidence: 99%

“…On the MRI examination, pituicytomas commonly presented as well-defined, solid, round or oval masses in the sellar region, with or without suprasellar extension. The tumors usually appeared hypointense-isointense on T1WI, low-moderately hyperintense on T2WI, and with homogenous or heterogeneouscontrast enhancement (6,13,25). Only four cases had solid cystic pituicytomas (2,7,26).…”

Section: Discussionmentioning

confidence: 99%

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Pituicytoma: A report of three cases and literature review

Yang

Liu

et al. 2016

Oncology Letters

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Abstract. Pituicytoma is a rare tumor of the sellar and suprasellar regions, arising from the pituicytes, which are specialized glial cells in the neurohypophysis and infundibulum. Due to its rarity, ambiguity persists over the diagnosis, management and prognosis of pituicytoma. The current study presents a case series of three patients, each with a histopathological diagnosis of pituicytoma. A summary of the clinical manifestations, radiological characteristics, histopathological features, treatment strategies and prognoses are presented. In addition, 78 cases of pituicytoma, identified in a search of the published literature in Pubmed, are profiled. Pituicytoma typically presents with dysfunction of the optic nerve and pituitary. The radiological characteristics are nonspecific; diagnosis is typically made on the basis of histopathological results. The tumor is slow growing and benign and is amenable to surgical treatment by gross total resection; subsequent tumor recurrence is rare. A definitive assessment of prognosis requires an extended follow-up in a larger cohort.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Pituicytoma: A report of three cases and literature review

Yang

Liu

et al. 2016

Oncology Letters

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“…In general, a pituicytoma should be suspected in patients presenting signs and/or symptoms of compression of the optic chiasm, infundibulum and/or pituitary gland, such as visual disturbances, headache, mildly elevated serum PRL, as well as features of hypopituitarism [2,4,15]. However, the clinical presentation of these intracranial depends on the size and the exact location of the lesions.…”

Section: Discussionmentioning

confidence: 99%

“…The tumor usually appears as a solid, well-circumscribed, non-infiltrative lesion occupying the sella turcica, the suprasellar space or both [1][2][3][4].…”

Section: Pituicytomamentioning

confidence: 99%

Pituitary image: pituicytoma

et al. 2014

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“…Including the present series, pituicytomas were clearly reported as soft in eight cases and firm only in five. According to the literature [11,27,28,40], 19 pituicytomas were reported to be very well vascularized with a high tendency to bleed at surgery. This is probably the main reason to explain the high number of subtotal resections.…”

Section: Discussionmentioning

confidence: 99%