Diagnostic accuracy of vesical imaging-reporting and data system (VI-RADS) for the detection of muscle-invasive bladder cancer: a meta-analysis

Feng, Yuebo; Zhong, Kai; Chen, Rui; Zhou, Weibin

doi:10.1007/s00261-022-03449-w

Cited by 10 publications

(6 citation statements)

References 42 publications

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“…21 To minimise false-negatives, a VI-RADS score of ≥3 is considered indicative of MIBC, with recent meta-analyses reporting high sensitivity (0.83-0.92), specificity (0.82-0.90), and area under the curve (AUC) (0.93-0.94) ranges. [21][22][23][24][25] mpMRI preceding TURBT could potentially lead to earlier MIBC recognition and treatment initiation. 26 VI-RADS may also serve as a non-invasive post-treatment monitoring and follow-up alternative to cystoscopy for BCa.…”

Section: Multiparametric Magnetic Resonance Imaging (Mpmri)mentioning

confidence: 99%

Comparison of staging MRI to re‐resection for localised bladder cancer: Narrative review

Klempfner,

Anderson

2024

BJUI Compass

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IntroductionBladder cancer (BCa) is characterised by high prevalence, multifocality, and frequent recurrence, imposing significant clinical and economic burdens. Accurate staging, particularly distinguishing non‐muscle‐invasive bladder cancer (NMIBC) from muscle‐invasive bladder cancer (MIBC) disease, is crucial for guiding treatment decisions. This narrative review explores the potential implications of incorporating multiparametric magnetic resonance imaging (mpMRI) and the Vesical Imaging Reporting Data System (VI‐RADS) into BCa staging, focusing on repeat transurethral resection of bladder tumour (re‐TURBT).MethodsA comprehensive search of PubMed, EMBASE, and MEDLINE databases identified studies published from 2018 to 2023 discussing mpMRI or VI‐RADS in the context of re‐TURBT for BCa staging. Studies meeting inclusion criteria underwent qualitative analysis.ResultsSix recent studies met inclusion criteria. VI‐RADS scoring, accurately predicted muscle invasion, aiding in NMIBC/MIBC differentiation. VI‐RADS scores of ≥3 indicated MIBC with high sensitivity and specificity. VI‐RADS potentially identified patients benefiting from re‐TURBT and those for whom it could be safely omitted.DiscussionmpMRI and VI‐RADS offer promising prospects for BCa staging, potentially correlating more closely with re‐TURBT and radical cystectomy histopathology than initial TURBT. However, validation and careful evaluation of clinical integration are needed. Future research should refine patient selection and optimise mpMRI's role in BCa management.ConclusionVI‐RADS scoring could revolutionise BCa staging, especially regarding re‐TURBT. There is potential that VI‐RADS correlates more with the histopathology of re‐TURBT and radical cystectomy than initial TURBT. While promising, ongoing research is essential to validate utility, refine selection criteria, and address economic considerations. Integration of VI‐RADS into BCa staging holds potential benefits for patients and health care systems.

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Section: Multiparametric Magnetic Resonance Imaging (Mpmri)mentioning

confidence: 99%

Comparison of staging MRI to re‐resection for localised bladder cancer: Narrative review

Klempfner,

Anderson

2024

BJUI Compass

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“…Even though the vast majority of published studies are single-institution and retrospective in nature, consistent data has recently been gained from prospective multicentre studies and systematic reviews. Five different meta-analyses on VI-RADS unanimously reported high sensitivity and specificity for predicting muscle invasion as well as a high diagnostic accuracy [13][14][15][16][17]. As summarised in Table 5, sensitivity, specificity and AUC ranged between 0.83-0.92, 0.82-0.90 and 0.93-0.94, respectively, when a cut-off score of VI-RADS ≥ 3 was used, and 0.77-0.78, 0.94-0.97 and 0.91-0.94, respectively, when a cut-off score of VI-RADS ≥ 4 was used.…”

Section: Diagnostic Performance Of Vi-radsmentioning

confidence: 99%

Diagnostic Protocol, Outcomes and Future Perspectives of the Vesical Imaging-Reporting and Data Systems (VI-RADS), a Narrative Review

Napolitano

Ippoliti²,

Fletcher

et al. 2023

Applied Sciences

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Bladder cancer (BC) is common worldwide, and has aggressive features and high rates of relapse despite treatments. Approximately 30% of patients present with muscle invasive disease, and therefore, high risk of metastasis. This review provides an overview of the state of the art for the ‘Vesical Imaging Reporting and Data System’ (VI-RADS). This scoring system presents a tool for the local staging of BC and has been validated across several institutions. We discuss the current application and the potential future clinical implications of VI-RADS in BC diagnosis, management and follow-up.

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“…T he rapid increase of numerous standardized imaging reporting and data systems such as liver, prostate, and vesicle imaging reporting and data systems (LI-RADS, PI-RADS, and VI-RADS, respectively) has further elucidated the limitations of subjective human interpretation in terms of reproducibility and accuracy. [1][2][3][4] In an effort to improve upon these inherent limitations there has been ongoing research in the field of quantitative imaging biomarkers. These biomarkers, derived from the image data itself have shown great potential in answering numerous clinical questions.…”

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confidence: 99%

“…In a meta-analysis of 19 studies a VI-RADS score of 4 was shown to predict muscle invasion with 78% sensitivity and 96% specificity. 3 A meta-analysis exploring VI-RADS inter-reader agreement in VI-RADS showed Kappa varying from 0.45 to 0.96 and averaging 0.76 in 19 studies. 4 In spite of the relatively high accuracy and inter-reader agreement as compared to the more traditional, invasive approach of TURBT, there remains plenty of room for improvement.…”

mentioning

confidence: 99%

“…VI‐RADS employs a five point scale ranging from VI‐RADS =1, definitely not muscle invading, to VI‐RADS = 5, definitely muscle invading. In a meta‐analysis of 19 studies a VI‐RADS score of 4 was shown to predict muscle invasion with 78% sensitivity and 96% specificity 3 . A meta‐analysis exploring VI‐RADS inter‐reader agreement in VI‐RADS showed Kappa varying from 0.45 to 0.96 and averaging 0.76 in 19 studies 4 .…”

mentioning

confidence: 99%

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Editorial for “Detecting Muscle Invasion of Bladder Cancer: An Application of Diffusion Kurtosis Imaging Ratio and Vesical Imaging‐Reporting and Data System”

Prince,

Shaish

2023

Magnetic Resonance Imaging

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Diagnostic accuracy of vesical imaging-reporting and data system (VI-RADS) for the detection of muscle-invasive bladder cancer: a meta-analysis

Cited by 10 publications

References 42 publications

Comparison of staging MRI to re‐resection for localised bladder cancer: Narrative review

Comparison of staging MRI to re‐resection for localised bladder cancer: Narrative review

Diagnostic Protocol, Outcomes and Future Perspectives of the Vesical Imaging-Reporting and Data Systems (VI-RADS), a Narrative Review

Editorial for “Detecting Muscle Invasion of Bladder Cancer: An Application of Diffusion Kurtosis Imaging Ratio and Vesical Imaging‐Reporting and Data System”

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