2022
DOI: 10.1016/j.diagmicrobio.2022.115635
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Diagnostic accuracy of rapid antigen test for COVID-19 in an emergency department

Abstract: Use of antigen tests for the diagnosis of COVID-19 has become widespread. The aim of this study was to evaluate the diagnostic accuracy of the nasopharyngeal rapid antigen diagnostic (RAD) immunoassay LumiraDx UK in an Emergency Department (ED). All patients admitted to our ED between November 11 and December 8, 2020 and had both a RAD test and a real-time-reverse-transcription-polymerase-chain-reaction (RT-PCR) test were enrolled. RAD was considered as the index test and RT-PCR test was used as the reference … Show more

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Cited by 10 publications
(7 citation statements)
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“… In patients with signs and symptoms compatible with COVID-19, we suggest the use of laboratory based NAAT in nasopharyngeal samples versus rapid antigen detection testing in nasopharyngeal samples for the diagnosis of COVID-19. Weak against Very low [ 4 , 5 , 16 , 106 , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , 6 , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , 8 , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , 10 , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] , [54] , [55] , 11 , [56] , [57] , [58] , [59] , [60] , [61] , [62] , [63] ...…”
Section: Questions Addressed By the Guideline Updatementioning
confidence: 99%
See 1 more Smart Citation
“… In patients with signs and symptoms compatible with COVID-19, we suggest the use of laboratory based NAAT in nasopharyngeal samples versus rapid antigen detection testing in nasopharyngeal samples for the diagnosis of COVID-19. Weak against Very low [ 4 , 5 , 16 , 106 , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , 6 , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , 8 , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , 10 , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] , [54] , [55] , 11 , [56] , [57] , [58] , [59] , [60] , [61] , [62] , [63] ...…”
Section: Questions Addressed By the Guideline Updatementioning
confidence: 99%
“… In asymptomatic people, we suggest the use of laboratory-based NAAT in nasopharyngeal samples versus rapid antigen testing in nasopharyngeal samples for the diagnosis of COVID-19. Weak against Low [ 11 , 18 , 38 , 43 , 44 , 46 , 47 , 49 , 50 , [54] , [55] , [56] , 20 , 57 , 65 , 67 , 68 , 70 , 71 , 77 , 81 , 83 , 86 , 22 , 87 , 90 , 92 , 94 , 99 , 102 , 113 , 155 , 158 , 160 , 24 , [161] , [162] , [163] , 165 , 168 , 170 , [172] , [173] , [174] , [175] , 28 , [176] , [177] , [178] , [179] , [180] , [181] , [182] , [183] , [29] , [30] ...…”
Section: Questions Addressed By the Guideline Updatementioning
confidence: 99%
“…However, spectrometry and spectroscopy are not portable devices and need a supporting ecosystem, such as a controlled room and a well-trained operator. In biology science, RT-PCR (realtime polymerase chain reaction) technique has been used widely to quantify and detect specific microorganisms in environmental samples 16,17) . However, this technique needs supporting technology (e.g., special laboratories, specific rooms, reagents, and other devices) and trained operators.…”
Section: Introductionmentioning
confidence: 99%
“…Duyarlılıkları, özgüllükleri, pozitif öngörü değeri (PPV) ve negatif öngörü değeri (NPV) farklı birçok hızlı antijen testi bulunmaktadır. Duyarlılık ve özgüllük; çalışma popülasyonunun (yaş, semptom varlığı veya yokluğu) özelliği, antijen testinin kullanım amacı, örneklerin nereden alındığı (oral, nazal, nazofarengeal gibi) ve kullanılan kite göre değişmektedir [13][14][15][16]. Pozitif ve negatif öngörü değeri ise özellikle hastalığın toplumdaki prevalansına göre değişiklik göstermektedir [17].…”
Section: Introductionunclassified