2014
DOI: 10.1097/cnd.0000000000000019
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Diagnostic Accuracy of Qualitative Versus Quantitative Tuning Forks

Abstract: Objective To assess the diagnostic accuracy of the Rydel-Seiffer vs. the qualitative 128 Hz tuning fork for detecting axonal neuropathy. Methods 100 consecutive patients seen at the Neurology Outpatient Electromyography (EMG) clinic at a major academic center were recruited and consented for this study. Study personnel who were blinded to results of nerve conduction studies, collected data on vibratory perception with both tuning forks at bilateral (a) great toe, and (b) distal inter-phalangeal joint on the … Show more

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Cited by 20 publications
(13 citation statements)
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“…However, the definition of normal CTF vibration threshold was not clearly stated in their article; also, the “ability to perceive vibration” per se would not be adequate to determine the degree of vibration perception to be normal. Recently, Lai et al . reported that they found no statistically significant difference in the sensitivity of the CTF and the RSTF in detecting axonal neuropathy, yet the sensitivity of their results was found to be low with both tuning forks, at 20% and 26%, respectively.…”
Section: Discussionmentioning
confidence: 96%
“…However, the definition of normal CTF vibration threshold was not clearly stated in their article; also, the “ability to perceive vibration” per se would not be adequate to determine the degree of vibration perception to be normal. Recently, Lai et al . reported that they found no statistically significant difference in the sensitivity of the CTF and the RSTF in detecting axonal neuropathy, yet the sensitivity of their results was found to be low with both tuning forks, at 20% and 26%, respectively.…”
Section: Discussionmentioning
confidence: 96%
“…This is done by placing the examiner's finger on the opposite surface of the joint being tested from the tuning fork, and noting if the vibration persists after the patient no longer senses it, or assessing the patient's threshold against the examiners, by applying the tuning fork to their finger. [23] The quantitative method involves noting the duration of perceived vibration using a stopwatch. In order to standardize the stimulus, the examiner must strike the 128-Hz tuning fork against the palm of the free hand just hard enough to make the metal ends meet to produce a metallic clanging sound.…”
Section: Discussionmentioning
confidence: 99%
“…For screening studies, especially when aiming to describe the frequency of polyneuropathy in the unselected general population, a high sensitivity is important in order not to miss any cases. Studies have shown that this is often not optimal for single test, such as monofilament or tuning fork examination (Perkins et al , ; Wang et al , ; Lai et al , ) . Moreover, distal sensory loss can also be found in healthy people without other signs of polyneuropathy, especially in the elderly (Vrancken et al , ) .…”
Section: Discussionmentioning
confidence: 99%