Diagnostic Accuracy of Mammography, Clinical Examination, US, and MR Imaging in Preoperative Assessment of Breast Cancer

Abstract

In nonfatty breasts, US and MR imaging were more sensitive than mammography for invasive cancer, but both MR imaging and US involved risk of overestimation of tumor extent. Combined mammography, clinical examination, and MR imaging were more sensitive than any other individual test or combination of tests.

The impact of preoperative MRI on breast-conserving surgery of invasive cancer: a comparative cohort study

“…Some of these considerations also hold for DCIS. Moreover, variable sensitivity of MRI for the detection of pure DCIS has been observed in other studies [10,[47][48][49][50].…”

“…Conventional imaging by mammography and ultrasonography fails to accurately assess tumor extent in approximately one-third of patients eligible for BCT [7]. Several studies reported a higher sensitivity of contrastenhanced magnetic resonance imaging (CE MRI) to detect invasive breast cancer and to visualize disease extent compared to the standard workup using conventional imaging [8][9][10][11]. These observations have led to changes in the surgical management of patients [12][13][14][15][16][17].…”

Quantitative diffusion weighted imaging for differentiation of benign and malignant breast lesions: The influence of the choice of b‐values

“…MRI of the breast has obtained a prominent role in clinical practice because of its high sensitivity for detecting invasive breast tumors (1)(2)(3). However, the specificity of DCE MRI of the breast, is substantially lower.…”

“…However, the specificity of DCE MRI of the breast, is substantially lower. It was shown to reach approximately 70% (1)(2)(3). Many different strategies have been proposed to increase the specificity such as calculating pharmacokinetic contrast parameters (4), T2*-weighted perfusion imaging (5) and MR spectroscopy (5).…”

A Comparison of Logistic Regression Analysis and an Artificial Neural Network Using the BI-RADS Lexicon for Ultrasonography in Conjunction with Introbserver Variability

“…In addition, these improvements have allowed expansion of the indications for use of breast ultrasound (US), including tumor differentiation, preoperative staging, follow-up after cancer treatment, and interventional diagnosis [8][9][10][11].…”