2022
DOI: 10.1007/s00520-022-07233-w
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Diagnostic accuracy of general dermatologists and supportive oncodermatologists for biopsied cutaneous immune-related adverse events

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Cited by 2 publications
(2 citation statements)
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“…Evaluation by a dermatologist was associated with better outcomes, and ICI retrial is a likely important contributing factor, returning to the connection between ciRAEs and survival highlighted above. Additional work has highlighted that even greater training and experience can improve specificity, where supportive oncodermatologists, in particular, have increased diagnostic accuracy compared to general dermatologists in the evaluation of biopsied cirAEs 53 . The study led by Thompson et al used billing and pathology requisition codes to retrospectively identify patients at Mass General Brigham/Dana‐Farber Cancer Institute who received anti‐PD‐1/PD‐L1 therapy between 2010 and 2019 and subsequently developed a cirAE that was biopsied by any dermatologist.…”
Section: Importance Of Dermatologic Evaluation In Patient Outcomesmentioning
confidence: 99%
“…Evaluation by a dermatologist was associated with better outcomes, and ICI retrial is a likely important contributing factor, returning to the connection between ciRAEs and survival highlighted above. Additional work has highlighted that even greater training and experience can improve specificity, where supportive oncodermatologists, in particular, have increased diagnostic accuracy compared to general dermatologists in the evaluation of biopsied cirAEs 53 . The study led by Thompson et al used billing and pathology requisition codes to retrospectively identify patients at Mass General Brigham/Dana‐Farber Cancer Institute who received anti‐PD‐1/PD‐L1 therapy between 2010 and 2019 and subsequently developed a cirAE that was biopsied by any dermatologist.…”
Section: Importance Of Dermatologic Evaluation In Patient Outcomesmentioning
confidence: 99%
“…1,2 La incidencia mundial de cáncer en la población pediátrica se reporta en 18.7/100,000 niños; 3 siendo las manifestaciones dermatológicas frecuentes y asociadas específicamente a los diferentes tipos de terapias utilizadas en el tratamiento; las cuales se manifiestan como reacciones que involucran piel y faneras. 4,5 Entre los principales eventos dermatológicos adversos descritos en el paciente pediátrico con diagnóstico oncológico ya sea secundario a terapia dirigida o quimioterapia citotóxica, se incluyen pero no se limitan a erupciones cutáneas, xerosis, urticaria, prurito, mucositis, alopecia, lesiones proliferativas de la piel, despigmentación de la piel y el cabello, síndrome de eritrodisestesia palmoplantar mano-pie, y reacción mano-piepiel, entre otras; [6][7][8] Estos eventos en la mayoría de los casos no representan riesgo de muerte para el paciente, no obstante, tienen el potencial de implicar graves deficiencias en la calidad de vida y las modificaciones de las dosis o interrupción de la terapia contra el cáncer que además puede afectar el resultado clínico; 6 por lo que el apoyo a través de la oncodermatología es de importancia, esta especialidad es un campo en crecimiento que brinda tratamiento y atención preventiva a estos pacientes; 9 con el propósito de prevenir manifestaciones graves que podrían RESUMEN. Antecedentes: Los pacientes oncológicos pediátricos pueden desarrollar lesiones dermatológicas secundario a terapia antineoplásica, afectando piel, cabello y uñas.…”
Section: Introductionunclassified