Diagnostic accuracy of FEV1/forced vital capacity ratio z scores in asthmatic patients

Lambert, Allison; Drummond, M. Bradley; Wei, Christine; Irvin, Charles G.; Kaminsky, David A.; McCormack, Meredith C.; Wise, Robert A.

doi:10.1016/j.jaci.2015.02.027

Cited by 12 publications

(8 citation statements)

References 14 publications

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“…4 D,E). FEV 1 to FVC ratios less than 80% have been highly correlated with obstructive lung disease due to a greater decrease in FEV 1 than FVC 20 , 21 . As such, it was ensured that the ratio of FEV 1 to FVC was > 80% for all patients, with a mean of 95.9% in the cohort.…”

Section: Resultsmentioning

confidence: 99%

A wearable eddy current based pulmonary function sensor for continuous non-contact point-of-care monitoring during the COVID-19 pandemic

Shahrestani

Chou

Shang

et al. 2021

Sci Rep

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Pulmonary function testing (PFT) allows for quantitative analysis of lung function. However, as a result of the coronavirus disease 2019 (COVID-19) pandemic, a majority of international medical societies have postponed PFTs in an effort to mitigate disease transmission, complicating the continuity of care in high-risk patients diagnosed with COVID-19 or preexisting lung pathologies. Here, we describe the development of a non-contact wearable pulmonary sensor for pulmonary waveform analysis, pulmonary volume quantification, and crude thoracic imaging using the eddy current (EC) phenomenon. Statistical regression analysis is performed to confirm the predictive validity of the sensor, and all data are continuously and digitally stored with a sampling rate of 6,660 samples/second. Wearable pulmonary function sensors may facilitate rapid point-of-care monitoring for high-risk individuals, especially during the COVID-19 pandemic, and easily interface with patient hospital records or telehealth services.

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Section: Resultsmentioning

confidence: 99%

A wearable eddy current based pulmonary function sensor for continuous non-contact point-of-care monitoring during the COVID-19 pandemic

Shahrestani

Chou

Shang

et al. 2021

Sci Rep

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“…The most clinically useful values are FEV 1 /FVC which may be indicative of obstructive lung disease when <0.70, a category to which some asthma patients may ascribe. However, this ratio is neither sensitive enough nor accurate enough for diagnosis [ 23 ]. FEV 1 % and FVC% values provide clinical information within the context of factors known to impact lung function (e.g., height, age, and gender).…”

Section: Methodsmentioning

confidence: 99%

Milk Consumption and Respiratory Function in Asthma Patients: NHANES Analysis 2007–2012

Sveiven

Bookman

et al. 2021

Nutrients

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Per the Centers for Diseases Control and Prevention, asthma prevalence has steadily risen since the 1980s. Using data from the National Health and Nutrition Examination Survey (NHANES), we investigated associations between milk consumption and pulmonary function (PF). Multivariable analyses were performed, adjusted for a priori potential confounders for lung function, within the eligible total adult population (n = 11,131) and those self-reporting asthma (n = 1,542), included the following variables: milk-consumption, asthma diagnosis, forced vital capacity (FVC), FVC%-predicted (%), forced expiratory volume in one-second (FEV1), FEV1% and FEV1/FVC. Within the total population, FEV1% and FVC% were significantly associated with regular (5+ days weekly) consumption of exclusively 1% milk in the prior 30-days (β:1.81; 95% CI: [0.297, 3.325]; p = 0.020 and β:1.27; [0.16, 3.22]; p = 0.046). Among participants with asthma, varied-regular milk consumption in a lifetime was significantly associated with FVC (β:127.3; 95% CI: [13.1, 241.4]; p = 0.002) and FVC% (β:2.62; 95% CI: [0.44, 4.80]; p = 0.006). No association between milk consumption and FEV1/FVC was found, while milk-type had variable influence and significance. Taken together, we found certain milk consumption tendencies were associated with pulmonary function values among normal and asthmatic populations. These findings propound future investigations into the potential role of dairy consumption in altering lung function and asthma outcomes, with potential impact on the protection and maintenance of pulmonary health.

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“…The primary outcome was lung function. It was assessed by forced expiratory volume in one second (FEV 1 ), [ 25 ] which is a marker utilized to measure lung function and can help to monitor the COPD for patients over time; and FEV 1 /forced vital capacity (FVC), [ 26 ] which is used to diagnosis the COPD with normal values of approximately 80%. It represents the ratio of an individual's vital capacity that they can expire in FEV 1 to the full, and FVC.…”

Section: Methodsmentioning

confidence: 99%

A retrospective study of Yiqibushenhuoxue decoction for the treatment of chronic obstructive pulmonary disease

Tian

Wang

et al. 2018

Medicine

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This retrospective study aimed to investigate the effect and safety of Yiqibushenhuoxue decoction (YQBSHXD) for the treatment of chronic obstructive pulmonary disease (COPD).This study involved 120 cases of patients with COPD. These cases were assigned to an intervention group and a control group equally, 60 subjects each group. Patients in both groups underwent Salmeterol. In addition, the cases in the intervention group also received YQBSHXD. All cases received a total of 12 weeks treatment. The primary outcome of lung function was measured by forced expiratory volume in 1 second (FEV1), and FEV1/forced vital capacity (FVC). The secondary outcomes included severity of dyspnea on exertion, evaluated by 6-minute walk test (6MWT) with measurement of 6-minute walk distance (6MWD); and quality of life, assessed by the St. George's Respiratory Questionnaire (SGRQ). In addition, adverse events (AEs) were also recorded in this study. All outcome measurements were assessed before and after 12-week treatment.After 12-week treatment, cases in the intervention group underwent YQBSHXD did not show better outcome in lung function improvement, measured by the FEV1 (P = .11), and FEV1/FVC (P = .15), compared with those in the control group. However, YQBSHXD may help to alleviate the severity of dyspnea on exertion, as measured by 6MWD (P = .03), and to improve the quality of life, as assessed by the SGRQ (P < .01). Additionally, no significant differences in AEs were detected between the 2 groups.The results of this study showed that YQBSHXD may help to manage COPD after 12-week treatment, although the lung function has not been improved.

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Diagnostic accuracy of FEV1/forced vital capacity ratio z scores in asthmatic patients

Abstract: Background-The FEV 1 /FVC ratio is used as a criterion for airflow obstruction; however, the test characteristics of spirometry in the diagnosis of asthma are not well established. The accuracy of a test depends upon the pre-test probability of disease.

Cited by 12 publications

References 14 publications

A wearable eddy current based pulmonary function sensor for continuous non-contact point-of-care monitoring during the COVID-19 pandemic

A wearable eddy current based pulmonary function sensor for continuous non-contact point-of-care monitoring during the COVID-19 pandemic

Milk Consumption and Respiratory Function in Asthma Patients: NHANES Analysis 2007–2012

A retrospective study of Yiqibushenhuoxue decoction for the treatment of chronic obstructive pulmonary disease

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