Diagnostic accuracy of EUS in the local staging of primary gastric lymphoma: Results of a prospective, multicenter study comparing EUS with histopathologic stage

Role of the Endoscopic Ultrasonography in the Management of Gastric Lymphomas: Our Experience and Review of Literature

“…First publications on the reliability of EUS in staging of PGL raised during the early '90's (Caletti et al, 1993) reported an accuracy of 80-92% and 77-90% for T and N stage respectively. These data were not confirmed by a successive study (Fischbach et al, 2002), involving 34 centers that reported an accuracy of 59% in detecting early stages and 71% in detecting the nodes involvement. These differences are probably due to the fact that EUS is an operator-dependent technique (Janssen, 2009).…”

“…In these trials, patients with DLBCL that achieved complete remission have shown no relapse of disease or lymphoma-related death, meanwhile patients with MALT lymphoma, without high-grade component, showed a relapse rate of 13% in a 70 months follow-up period. Similarly, the German group, in a multicentric prospective study involving 417 patients (Fischbach et al, 2002), demonstrated that recurrence of disease occurs in 3.9% of MALT lymphoma and 4.7% of DLBCL. Additionally, in another multicentric trial on early stage MALT lymphoma, patients with histologically proven residual disease, have shown no recurrence of disease, except one of them that presented a transformation to DLBCL.…”

Role of endoscopic ultrasonography with and without fine needle aspiration cytology in the diagnosis and staging of lymphoma

“…However, EUS is extremely accurate in differentiating early invasion (T1 mucosal or submucosal, EI1 of Ann Arbor classification) from T2-T4 (EI2) or TxN1 (EII1) [21] . Diagnostic accuracy for T staging has ranged between 80% and 90% across the studies [22,23] , whereas for N stage, it ranges between 71% and 90% [22,24] . Accuracy is even higher when EUS is associated with FNA and FC being reported as high as 97% [25] .…”

Magenlymphome – noch eine chirurgische Erkrankung?

“…Für die Magenlymphome nimmt darü-ber hinaus der endoskopische Ultraschall einen besonderen Stellenwert ein, erlaubt er doch als einziges bildgebendes Verfahren eine Differenzierung der Magenwandschichten und die Erfassung perigastraler Lymphome, das heißt die prognostisch bedeutsame Zuordnung zu den Stadien I1, I2 und II1 [6]. Für die Stadieneinteilung wird üblicherweise nach wie vor die AnnArbor-Klassifikation in ihrer Modifikation nach Musshoff und unter Berücksich-tigung der Differenzierung des Stadiums I nach Radaskiewicz benutzt.…”