Diagnostic Accuracy of Dual-Source Computed Tomography in the Diagnosis of Coronary Artery Disease

Johnson, Thorsten R. C.; Nikolaou, Konstantin; Busch, Stephanie; Leber, Alexander; Becker, Alexander; Wintersperger, Bernd J.; Rist, Carsten; Knez, Andreas; Reiser, Maximilian; Becker, Christoph

doi:10.1097/rli.0b013e31806907d0

Cited by 137 publications

(62 citation statements)

References 32 publications

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“…It is particularly interesting that the diagnostic accuracy of CAS for patients who had calcium scores >400, decreased mildly compared to patients with calcium scores <400 in this study. Beam-hardening and blooming artifacts have made it difficult to assess the degree of luminal narrowing in CCTA with DSCT, as well as 64-slice MDCT, when heavily calcified plaques are present (8,10,12,25,26). Based on invasive coronary angiography, diagnostic errors are usually attributable to the overestimation of the degree of stenosis, while the diagnostic accuracy ranged from 67% to 85% (13,25,27).…”

Section: Discussionmentioning

confidence: 99%

“…The detection of stenosis was found to be >50% on a per-segment basis, while these same measurements were 88-95%, 92-99%, 68-81%, and 97-99%, respectively for DSCT (1,(12)(13)(14)(15)(16)(17)(18).…”

mentioning

confidence: 90%

“…The results of the CCTA detection of significant stenoses (lesions >50%) were compared with the results of conventional coronary angiography according on a: (a) per-segment basis, comparing each segment in every vessel; (b) per-vessel basis, looking for the presence of significant lesions of the major coronary vessels; and (c) per-patient basis, looking for the presence of any significant stenotic vessel lesions in each patient (2,(12)(13)(14)(15)(16)(17)23).…”

Section: Comparisons and Evaluationsmentioning

confidence: 99%

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Diagnostic Accuracy of 64-slice Dual-source Computed Tomography in the Detection of Coronary Artery Stenosis based on Patient Heart Rate and Calcium Scores

Kim

Jin

Han

et al. 2010

J Korean Soc Radiol

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Purpose: To assess the diagnostic accuracy of dual-source computed tomography (DSCT) in the detection of coronary artery stenosis (CAS) based on patient heart rate and calcium scores. Materials and Methods: This study included 102 patients (46 male, 56 female; mean age 64.1 ± 10.6 years; age range 37-92 years) with chest pain and who underwent DSCT as well as invasive coronary angiography. Patients were classified into three groups according to mean heart rate (<70 bpm, 70-90 bpm, and >90 bpm) and also classified in three groups according to Agatston calcium scores (<100, 100-400, and >400). Results: For patients with a mean heart rate < 70 bpm, the sensitivity, specificity, PPV, NPV, and diagnostic accuracy of DSCT on a per-vessel basis were 98.5%, 98.2%, 93.6%, 99.1%, and 97.9%, respectively, 99.2%, 99.2%, 97.4%, 99.5%, and 99%, respectively, for 70-90 bpm; and 91.7%, 97.9%, 88.5%, 96.7%, and 95.7%, respectively, for >90 bpm. For calcium scores <100, the sensitivity, specificity, PPV, NPV, and diagnostic accuracy of DSCT on a per-vessel basis were 97.2%, 99.0%, 97.0%, 99.3%, and 98.6%, respectively, 98.5%, 99.5%, 96.2%, 99.4%, and 99.0%, respectively, for calcium scores 100-400, and 95.8%, 97.0%, 87.4%, 97.2%, and 95.6%, respectively, for calcium scores >400. Conclusion: DSCT showed a high diagnostic accuracy and negative predictive value, regardless of heart rate and calcium score.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 90%

Section: Comparisons and Evaluationsmentioning

confidence: 99%

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Diagnostic Accuracy of 64-slice Dual-source Computed Tomography in the Detection of Coronary Artery Stenosis based on Patient Heart Rate and Calcium Scores

Kim

Jin

Han

et al. 2010

J Korean Soc Radiol

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“…Çok kesitli BT cihazlarında 64 kesittten 128 ve 256 kesitliye, hatta 320 kesitliye varan sistemlerin gelişmesiyle birlikte tek gantri dönüş süresi içerisinde tüm kalbin görüntülenmesi mümkün hale gelmiştir [47][48][49]. Altmış dört kesitli BT'lerde dedektör kapsama alanı maksimum 4 cm (64x0,625 mm) iken, 256 kesitlide 12,8 cm'ye (256x0,5 mm), 320 kesitlide 16 cm'ye (320x05 mm) ulaşmaktadır.…”

Section: Koroner Arter Hastalığının Tespitinde Bt Teknolojisinin Geliunclassified

Koroner Arter Hastalığı

Koplay¹,

Erol²

2013

Trd Sem

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“…However, a non-systematic sample of 10 studies which were excluded from the review at the full-paper-screening stage and which reported accuracy data in their abstracts indicated sensitivity and specificity estimates of 87-100% and 73-98%, respectively. [116][117][118][119][120][121][122][123][124][125] None of the categories of difficult-to-image patients considered in this review was evaluated in large numbers of studies; the maximum was eight studies for patients with HHRs. Data were particularly sparse for obese patients and patients with previous bypass graft(s).…”

Section: Clinical Effectivenessmentioning

confidence: 99%

A systematic review and economic evaluation of new-generation computed tomography scanners for imaging in coronary artery disease and congenital heart disease: Somatom Definition Flash, Aquilion ONE, Brilliance iCT and Discovery CT750 HD

Westwood

Burgers

et al. 2013

Health Technol Assess

142

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Reports are published in Health Technology Assessment (HTA) if (1) they have resulted from work for the HTA programme, and (2) they are of a sufficiently high scientific quality as assessed by the reviewers and editors.Reviews in Health Technology Assessment are termed 'systematic' when the account of the search appraisal and synthesis methods (to minimise biases and random errors) would, in theory, permit the replication of the review by others. HTA programmeThe HTA programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care.The journal is indexed in NHS Evidence via its abstracts included in MEDLINE and its Technology Assessment Reports inform National Institute for Health and Clinical Excellence (NICE) guidance. HTA research is also an important source of evidence for National Screening Committee (NSC) policy decisions.For more information about the HTA programme please visit the website: http://www.hta.ac.uk/ This reportThe research reported in this issue of the journal was commissioned and funded by the HTA programme on behalf of NICE as project number 10/107/01. The protocol was agreed in February 2011. The assessment report began editorial review in June 2011 and was accepted for publication in March 2012. The authors have been wholly responsible for all data collection, analysis and interpretation, and for writing up their work. The HTA editors and publisher have tried to ensure the accuracy of the authors' report and would like to thank the reviewers for their constructive comments on the draft document. However, they do not accept liability for damages or losses arising from material published in this report.This report presents independent research funded by the National Institute for Health Research (NIHR). The views and opinions expressed by authors in this publication are those of the authors and do not necessarily reflect those of the NHS, the NIHR, NETSCC, the HTA programme or the Department of Health. Published by the NIHR Journals Library, produced by Prepress Projects Ltd, Perth, Scotland (www.prepress-projects.co.uk). Abstract A systematic review and economic evaluation of newgeneration computed tomography scanners for imaging in coronary artery disease and congenital heart disease: Somatom Definition Flash, Aquilion ONE, Brilliance iCT and Discovery CT750 HD NIHR Journals Library

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Diagnostic Accuracy of Dual-Source Computed Tomography in the Diagnosis of Coronary Artery Disease

Abstract: The comparison of coronary DSCT with QCA shows a very robust image quality and a high diagnostic accuracy in a patient-based as well as a per-segment analysis. Maximal sensitivity and NPV in the per-patient analysis show the strength of the technique in ruling out significant CAD.

Cited by 137 publications

References 32 publications

Diagnostic Accuracy of 64-slice Dual-source Computed Tomography in the Detection of Coronary Artery Stenosis based on Patient Heart Rate and Calcium Scores

Diagnostic Accuracy of 64-slice Dual-source Computed Tomography in the Detection of Coronary Artery Stenosis based on Patient Heart Rate and Calcium Scores

Koroner Arter Hastalığı

A systematic review and economic evaluation of new-generation computed tomography scanners for imaging in coronary artery disease and congenital heart disease: Somatom Definition Flash, Aquilion ONE, Brilliance iCT and Discovery CT750 HD

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