Diagnosis, Therapy and Control of Diabetes Mellitus in Children and Adolescents

Neu, Andreas; Beyer, P; Bürger-Büsing, Jutta; Danne, Thomas; Etspüler, J.; Heidtmann, Bettina; Holl, Reinhard W.; Karges, Beate; Kieß, Wieland; Knerr, Ina; Kordonouri, Olga; Lange, Karin; Lepler, R.; Marg, W.; Näke, Andrea; Petersen, M.; Podeswik, Andreas; Stachow, Rainer; Sengbusch, Simone von; Wagner, Verena; Ziegler, Ralph; Holterhus, PM

doi:10.1055/s-0034-1366384

Cited by 9 publications

(7 citation statements)

References 93 publications

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“…Indication for CSII followed the clinical criteria of the German Clinical Practice Guidelines, namely, recurrent severe hypoglycemia, wide fluctuations in blood glucose levels, suboptimal diabetes control, pronounced dawn−/ dusk phenomenon, needle phobia, and also improvement of the young patient's motivation, the wish for more flexibility in mealtimes and daily routine, and patients' preference (not specified). Patients were transferred to CSII by a multidisciplinary diabetes team …”

Section: Methodsmentioning

confidence: 99%

Psychosocial benefits of insulin pump therapy in children with diabetes type 1 and their families: The pumpkin multicenter randomized controlled trial

et al. 2018

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Objective Continuous subcutaneous insulin infusion (CSII) is on the rise among pediatric patients with type 1 diabetes mellitus. Metabolic effects alone cannot explain this rising popularity. From the patient's perspective, the main benefits of CSII may be found in subjective psychosocial health outcomes (patient‐reported outcomes [PRO]). Subjects and Methods In a multicenter open randomized controlled trial, children and adolescents aged 6 to16 years currently treated with multiple daily injections (MDI) were randomized 1:1, stratified by center, to either starting with CSII immediately after the baseline interview or to continuing MDI while waiting 6 months for transmission to CSII. The primary outcomes were patient‐reported diabetes‐specific health‐related quality of life (DHRQOL) and diabetes burden of the main caregiver. Secondary outcomes were caregiver stress, fear of hypoglycemia, satisfaction with treatment, and HbA1c. Results Two‐hundred and eleven patients were randomized between February 2011 and October 2014, and 186 caregivers and 170 patients were analyzed using the intention‐to‐treat principle for primary outcomes. Children 8 to 11 years in the CSII group reported improved DHRQOL at follow‐up compared to MDI (median difference [MD] 9.5, 95% confidence interval [CI] 3.6‐16.7, P = 0.004). There were no treatment differences in the adolescent age‐group 12 to 16 years (MD 2.7; 95% CI −3.2‐9.5; P = 0.353). The main caregivers of the CSII group reported a significant decline of overall diabetes burden at follow‐up compared to the MDI group (MD 0; 95% CI −1‐0; P = 0.029). Secondary PROs also were in favor of CSII. Conclusions CSII has substantial psychosocial benefits. PROs demonstrate these benefits. Registered as NCT01338922 at http://clinicaltrials.gov

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Section: Methodsmentioning

confidence: 99%

Psychosocial benefits of insulin pump therapy in children with diabetes type 1 and their families: The pumpkin multicenter randomized controlled trial

et al. 2018

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“…The insulin-producing pancreatic beta cells are destroyed in individuals with T1DM resulting in lifetime dependence of exogenous insulin [2,3]. Type 1 diabetes, as a serious and lifelong disorder leads to a lot of systemic complications [4,5]. It may also affect physical and psychological health of children and their parents.…”

Section: Introduction ▼mentioning

confidence: 99%

“…Parents of diabetic children face a wide range of tasks including glucose monitoring, glycemic control, diet changes, and insulin administration; all of which are additional stressors for diabetic children and their families. Consequently, children with diabetes and their family members face psychological issues [4,6]. Depression is a common disorder in children and adolescents with T1DM with a 20 % prevalence rate compared to that of 7 % in those without diabetes [7,8].…”

Section: Introduction ▼mentioning

confidence: 99%

Quality of Life and Psychological Screening in Children with Type 1 Diabetes and their Mothers

Duru

Çivilibal

Elevli

2015

Exp Clin Endocrinol Diabetes

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This study aimed to assess the levels of depression in children with type 1 diabetes mellitus (T1DM) and evaluate the quality of life as well as levels of depression and anxiety of their mothers.30 children with T1DM (mean age: 12.9±2.9 years) and their mothers (mean age: 40.0±7.5 years) were included in the study. Control group consisted of 30 healthy children (mean age: 12.7±2.7 years) and their mothers (mean age: 39.8±7.2 years). The presence and severity of depressive symptoms in the children were evaluated using the Children's Depression Inventory (CDI). The short form 36-health survey (SF-36), the Beck Depression Inventory (BDI), and Spielberg's State-Trait Anxiety Inventory (STAI) were administered to all mothers.The children with T1DM had higher scores of depression compared to healthy children in the control group. The mothers of children with T1DM had significantly lower scores on all subscales of SF-36 except the bodily pain subscale. We observed a significant difference between groups in their BDI scores; the mean BDI score was higher in mothers of children with T1DM (p=0.004). There was a significant difference in STAI scores between groups. CDI scores positively correlated with the ages of and HgA1C levels in the children with T1DM. There was a positive correlation between CDI scores of children with T1DM and BDI scores of their mothers. In addition, CDI sores negatively correlated with the scores of vitality and social functioning subscales of SF-36.Our findings suggest screening for mental health issues and quality of life in diabetic children and their mothers.

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“…Studies claim that the planning of care in diabetes in schools helps in the control of blood sugar levels, improves confidence and minimizes the concern of both the family and the professionals of the educational institution 6 - 9 .…”

Section: Introductionmentioning

confidence: 99%

Translation, adaptation and validation the contents of the Diabetes Medical Management Plan for the Brazilian context

Torres

Chaves

Silva

et al. 2016

Rev. Latino-Am. Enfermagem

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Objective: to translate, adapt and validate the contents of the Diabetes Medical Management Plan for the Brazilian context. This protocol was developed by the American Diabetes Association and guides the procedure of educators for the care of children and adolescents with diabetes in schools. Method: this methodological study was conducted in four stages: initial translation, synthesis of initial translation, back translation and content validation by an expert committee, composed of 94 specialists (29 applied linguists and 65 health professionals), for evaluation of the translated version through an online questionnaire. The concordance level of the judges was calculated based on the Content Validity Index. Data were exported into the R program for statistical analysis: Results: the evaluation of the instrument showed good concordance between the judges of the Health and Applied Linguistics areas, with a mean content validity index of 0.9 and 0.89, respectively, and slight variability of the index between groups (difference of less than 0.01). The items in the translated version, evaluated as unsatisfactory by the judges, were reformulated based on the considerations of the professionals of each group. Conclusion: a Brazilian version of Diabetes Medical Management Plan was constructed, called the Plano de Manejo do Diabetes na Escola.

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Diagnosis, Therapy and Control of Diabetes Mellitus in Children and Adolescents

Cited by 9 publications

References 93 publications

Psychosocial benefits of insulin pump therapy in children with diabetes type 1 and their families: The pumpkin multicenter randomized controlled trial

Psychosocial benefits of insulin pump therapy in children with diabetes type 1 and their families: The pumpkin multicenter randomized controlled trial

Quality of Life and Psychological Screening in Children with Type 1 Diabetes and their Mothers

Translation, adaptation and validation the contents of the Diabetes Medical Management Plan for the Brazilian context

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