2014
DOI: 10.1016/j.diagmicrobio.2013.11.004
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Diagnosis of venous access port colonization requires cultures from multiple sites: should guidelines be amended?

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Cited by 11 publications
(8 citation statements)
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References 27 publications
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“…In contrast, among 24 positive TIVAP-cultures, nine were tip-culture negative, while the corresponding reservoirs and septa were culture positive, meaning that a large proportion of TIVAP-cultures (as high as 38 %) would have been false negative without reservoir culture. Thus, our study provides further evidence that culture of the TIVAP reservoir may increase the sensitivity and the accuracy of the test for a definitive diagnosis of TIVAP-related BSI and confirms previous observations that support the importance of reservoir culture in the diagnosis of TIVAP-related BSI [15,16,27]. From a practical point of view, in this study we separated the septum from the reservoir with the aid of scissors and tweezers.…”
Section: Discussionsupporting
confidence: 88%
See 1 more Smart Citation
“…In contrast, among 24 positive TIVAP-cultures, nine were tip-culture negative, while the corresponding reservoirs and septa were culture positive, meaning that a large proportion of TIVAP-cultures (as high as 38 %) would have been false negative without reservoir culture. Thus, our study provides further evidence that culture of the TIVAP reservoir may increase the sensitivity and the accuracy of the test for a definitive diagnosis of TIVAP-related BSI and confirms previous observations that support the importance of reservoir culture in the diagnosis of TIVAP-related BSI [15,16,27]. From a practical point of view, in this study we separated the septum from the reservoir with the aid of scissors and tweezers.…”
Section: Discussionsupporting
confidence: 88%
“…Previous studies have compared different methods as diagnostic procedures for catheter culture, but such comparisons have rarely been reported for TIVAPs [15,16]. Therefore, more evidence is needed to identify the optimal method to recover micro-organisms from colonized catheters and decrease false negative results in the diagnosis of TIVAPrelated bloodstream infections.…”
Section: Introductionmentioning
confidence: 99%
“…For example, the 120-min cutoff is less accurate for Candida sp. and S. aureus [61]. The accuracy of the technique is based on sampling the same amount of blood from both the catheter and peripherally.…”
Section: Diagnosis Of Crbsi With Catheter In Placementioning
confidence: 99%
“…Bouza et al. reported that combination of cultures of multiple sites of TIVAP was the best technique to diagnose TIVAP colonization . Another frequent challenge is to diagnose CRBSI in patients who already received systemic antibiotics, leading to false‐negative results of blood or catheter tip culture.…”
Section: Diagnosismentioning
confidence: 99%
“…Indeed, one study reported that after TIVAP removal, tip culture was only 46% sensitive, whereas septum culture was 93.3% sensitive for confirming the diagnosis of TIVAP-related BSI (74). Bouza et al reported that combination of cultures of multiple sites of TIVAP was the best technique to diagnose TIVAP colonization (75,76). Another frequent challenge is to diagnose CRBSI in patients who already received systemic antibiotics, leading to false-negative results of blood or catheter tip culture.…”
Section: Diagnosismentioning
confidence: 99%