Diagnosis of uterine cervix cancer using Müller polarimetry: a comparison with histopathology

Mueller polarimetric imaging for surgical and diagnostic applications: a review

“…As displayed in Figure 1(a) which is an illustrative example to exhibit the advantages of polarimetric imaging over polarization insensitive imaging, significant differences in tissue linear retardance and depolarization in healthy and precancerous regions of human cervix were observed [12] and it was noted that cervical tissue depolarization is capable of revealing morphological changes in the epithelium, with the retardance sensitive to the morphological changes in the stroma [19]. 62 % sensitivity and 64 % specificity were achieved by optimizing a simple tissue retardance threshold [18]. Another application demonstrated the ability of polarimetry to characterize the micro-organizational state of the myocardium and to monitor regenerative treatments of myocardial infarction [145].…”

“…The characteristic polarization information of interest is carried by a 4 3 4 matrix named a Mueller matrix and this can be experimentally obtained from Mueller polarimetry and polarimetric imaging. In recent years, an increasing number of biomedical applications of Mueller polarimetric imaging techniques have been proposed [5], e. g. oral cancerous legion detection [13], cervical cancer and colon cancer detection and staging [12,[14][15][16][17][18][19], assessment of cancer therapy [20], partial bladder obstruction diagnosis [21], guiding mass spectrometry for instant pathology [22], characterizing collagen fibres [23], and these have demonstrated advantages over polarization blind imaging.…”