Diagnosis of tuberculosis and risk factors involved

Khanum, Hamida; Sultana, Rumana; Dhar, Ripon Chandra

doi:10.3329/bjz.v40i2.14315

Cited by 6 publications

(10 citation statements)

References 12 publications

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“…Pulmonary tuberculosis is the major cause of morbidity and mortality which is prevalent in the developing world. Khanum et al 2 study revealed that pulmonary tuberculosis (74.51%) was more prevalent than extrapulmonary tuberculosis (25.49%). If left untreated, a person with active tuberculosis infect an average of 10-15 other people every year.…”

Section: Introductionmentioning

confidence: 94%

Vitamin D status in Pulmonary Tuberculosis : a case control study

Sah

Biswas

et al. 2022

Bangabandhu Sheikh Mujib Medical University Journal

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Pulmonary tuberculosis is the major cause of morbidity and mortality in the developing world. In South Asia, 80% of the apparently healthy population have vitamin D deficiency (<20 ng/mL). An association between vitamin D levels with tuberculosis has been described in several studies. But there are scarcities of studies carried out in Bangladesh to determine the association. This study, a case-control study with 2 years duration, determined and compared vitamin D concentration between pulmonary tuberculosis patients and healthy controls. Patients were recruited from the department of internal medicine, Bangabandhu Sheikh Mujib Medical University. All newly diagnosed patients of pulmonary tuberculosis who fulfiled the inclusion and exclusion criteria were selected as case; equal number of healthy subjects without pulmonary TB as control. Vitamin D level less than 20 ng/ml was considered deficiency; 21 to 29ng/ml as relative insufficiency and >30ng/ml as normal. Thirty partici- pants in each group were enrolled, from whom serum vitamin D concentration was measured, analyzed and interpreted. Mean serum vitamin D level was significantly low in case group than control group (p <0.05). The odds ratio corresponding to vitamin D deficiency in case group compared to control was 5.21 [95% CI (1.12 –27.53), (p= 0.015)]. Result indicates patients having vitamin D level <20 ng/ml has 5.21 times more risk to develop pulmonary tuberculo- sis. In conclusion, Vitamin D deficiency was significantly low in pulmonary tuberculo- sis patients and supplementation is required for them. BSMMU J 2021; 14(3): 85-91

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Section: Introductionmentioning

confidence: 94%

Vitamin D status in Pulmonary Tuberculosis : a case control study

Sah

Biswas

et al. 2022

Bangabandhu Sheikh Mujib Medical University Journal

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“…Tuberculosis is an infectious disease that is widely prevalent in Bangladesh, 1 with pulmonary tuberculosis being more prevalent than extra-pulmonary tuberculosis. 2 Despite this, there is scant literature on the influence of messages from policy makers and health workers on the sexual and reproductive health (SRH) of tuberculosis patients. Such scarcity is crucial to address when, despite incorporating SRH rights into policies, 3 there is meagre implementation and social recognition of these rights in Bangladesh.…”

Section: Introductionmentioning

confidence: 99%

Disciplining sexual and reproductive behaviour of tuberculosis patients in Bangladesh: a mixed method study exploring divergent messages

Barua

Driel

2021

Sexual and Reproductive Health Matters

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There is scant information on the instructions provided by health workers to patients diagnosed with tuberculosis and the implications these instructions have for sexual and reproductive health and rights and tuberculosis control in Bangladesh. This paper aims to draw attention to tuberculosis control guidelines and information dissemination practices that may need to be adapted to the living situations of those with tuberculosis. Data collection took place in the Monohardi and Narsingdi Sadar sub-districts in Narsingdi and the Mirpur slum in Dhaka, Bangladesh, between December 2015 and March 2016. We present findings from an analysis of four significant documents, 45 in-depth interviews (of current and former tuberculosis patients, their family members, and health workers), and two focus group discussions with health workers. The findings show that the official guidelines and policies hardly address sexual health or rights. During the treatment period, patients received mixed and inconsistent instructions from health workers on sexual intercourse, contraception, pregnancy, and living arrangements. The messages were interpreted differently based on who delivered and received them, and different instructions were provided to women and men. The instructions were not specific to the living situations of patients and therefore led to implementation challenges. Future interventions should ensure correct and consistent messaging, and policies should be adapted to the sexual needs of those infected with the disease.

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“…A National Tuberculosis Control Program (NTP) report states that the total number of TB patients increased from 57% to 61% between 2015 and 2016. It is also estimated that 25.51% of TB infections occur extrapulmonarily in Bangladesh (2). Worldwide, TB is the second highest infective cause of death after HIV (3).…”

Section: Introductionmentioning

confidence: 99%

18F FDG PET-CT Imaging in the Evaluation of Diagnosed Extra Pulmonary Tuberculosis

Zohra¹,

Begum²,

Akram³

et al. 2019

Bangladesh J. Nuclear Med.

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Objectives: Extra Pulmonary Tuberculosis (EPTB) presents with atypical symptoms and heterogeneous clinical features. Management of EPTB including diagnosis, localization, extension and monitoring treatment response of active disease is quite challenging. Moreover, localization of active disease, differentiation between active and latent disease by conventional methods is troublesome. So this study was done to evaluate the metabolic activity of active disease by 18F Flurodeoxyglucose (FDG) PET-CT in diagnosed cases of EPTB patients. Patients and methods: A total of 17 patients with EPTB were included in this study. FDG PET-CT scan was performed to evaluate the metabolic activity of tubercular lesions before anti-TB treatment. Clinical features, biochemical changes including ESR, WBC count, CRP, MT test and maximum standardized uptake value (SUVmax) of most intense FDG avid lesions and sizes were recorded in 18F FDG PET-CT scan. Results: All 17 patients (09 female, 08 male) had lymph node involvement, two had bone TB and two had abdominal TB. Active TB lesions showed increased FDG uptake in extra-pulmonary tubercular lesions in 16 patients. The mean SUVmax value of the involved lymph nodes were 9.4 ± 6.0 and the mean size (maximum diameter) 19.8 ± 10.4 mm (mean ± SD). One histologically proven EPTB patient had non avid lesions in FDG PET-CT scan. Conclusion: 18F FDG PET-CT scan plays an important role in the localization, extension and differentiation between active and latent TB. In this study, the metabolic activity and size of the involved tubercular lymph nodes were increased in active lesions. Increased FDG uptake in active tubercular lesions may help in treatment monitoring of EPTB. Non avid lesions in EPTB patients revealed suggested latent TB which can change further management plan. Although PET-CT is an expensive technology, application of this sophisticated imaging technique in atypical or doubtful cases of EPTB might modify the treatment plan significantly after proper evaluation of the disease status. , 18F FDG PET-CT scan will be helpful to evaluate the disease status and modification of treatment regime in non-responders cost-effectively. A nationwide large-scale study would be the better way for clinical validation. Bangladesh J. Nuclear Med. 22(1): 9-14, Jan 2019

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Diagnosis of tuberculosis and risk factors involved

Cited by 6 publications

References 12 publications

Vitamin D status in Pulmonary Tuberculosis : a case control study

Vitamin D status in Pulmonary Tuberculosis : a case control study

Disciplining sexual and reproductive behaviour of tuberculosis patients in Bangladesh: a mixed method study exploring divergent messages

18F FDG PET-CT Imaging in the Evaluation of Diagnosed Extra Pulmonary Tuberculosis

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