Background and Objectives: Preterm labour complicates 5-10% of pregnancies and is a leading cause of neonatal morbidity and mortality worldwide. It is a major public health problem in terms of loss of life, long-term disability (cerebral palsy, blindness, deafness, chronic lung disease) and health care costs both in the developing and the developed world.There is need for tocolytic therapy to reduce perinatal mortality and morbidity by delaying delivery at least for 48 hours to allow time for therapeutic effects of corticosteroids Methodology : This study was undertaken at Sri Siddhartha medical college and hospital research centre tumakuru between October 2017 to October 2019.76 Antenatal cases with gestational age 28weeks-37weeks as per the inclusion and exclusion criteria's who were admitted and clinically diagnosed as preterm labour were selected . The selected patients were treated with Nitro-glycerine patch Results : Success rate for acute tocolysis was 88.2%.Mean prolongation of pregnancy was 14.46 days and mean birth weight of babies was 2.19 kilograms. Most common side effect with Nitroglycerine patch was headache (5.3%).
Conclusion:Nitroglycerine patch is effective in suppression of preterm labor as short term tocolytic in prolongation of pregnancy. Nitroglycerine is well tolerated and safe for the mother and fetus with minor side effects