Diagnosis of non-immediate hypersensitivity to amoxicillin in children by skin test and drug provocation tests: A retrospective case-series study

Katoh, Yukiko; Natsume, Osamu; Matsunaga, Mayumi; Takayanagi, Fumitaka; Uchida, Hiroshi; Yasuoka, Ryuhei

doi:10.1016/j.alit.2021.07.009

Cited by 4 publications

(2 citation statements)

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“…On the DLST, the drug at 0.1, 1 or 10-fold of maximum plasma concentration was added to the lymphocytes separated from our patient's plasma. Lymphocytes were cultured for 72 h, and 3 H-thymidine was then added [14]. After culturing the lymphocytes for 16-18 h, radioactivity resulting from the uptake of 3 H-thymidine was measured by the cells during deoxyribonucleic acid (DNA) synthesis in counts per minutes (cpm).…”

Section: Case Reportmentioning

confidence: 99%

“…After culturing the lymphocytes for 16-18 h, radioactivity resulting from the uptake of 3 H-thymidine was measured by the cells during deoxyribonucleic acid (DNA) synthesis in counts per minutes (cpm). The SI was calculated as the ratio of proliferation (cpm) with the drug/proliferation (cpm) without the drug [14]. Abdominal ultrasound, computed tomography and magnetic resonance imaging results indicated acute liver injury (Figure 1).…”

Section: Case Reportmentioning

confidence: 99%

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A Case of Recent Liver Injury Induced by Benzbromarone

Ishii

Hoshino

Honda

et al. 2022

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A 39-year-old male had a stomachache for 10 days before abnormal liver function tests were detected by a local doctor. Then, he was referred to us and admitted to our hospital for examination and treatment of elevated transaminases. He had taken benzbromarone to treat his hyperuricemia for seven months, and we diagnosed him with benzbromarone-induced liver injury. After the termination of benzbromarone, he finally recovered from his illness. There are several reports about benzbromarone-induced liver injury. In conclusion, as periodic liver function tests seem not to be completely performed, clinicians should regularly monitor liver function tests in patients taking benzbromarone.

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Section: Case Reportmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%