“…Causes of arterial occlusion, including HHS, can be trauma, embolism and thrombus, arterial malformation, thoracic outlet syndrome and quadrilateral space syndrome (i.e., constriction), medium and small-vessel vasculitis, Raynaud’s disease, antiphospholipid antibody syndrome, myeloproliferative disorders, sclerosis, hypercoagulable states, and immune-mediated/inflammatory disease [ 3 , 4 ]. Miyayama et al reported two patients with heart disease and thrombosis of the upper extremity, which accounted for 19% of the total thrombosis [ 5 ].…”