Diagnosis of Helicobacter Pylori Infection With A Stool Assay: Is It Useful After Eradication Treatment?

Comparison of two Different Stool Antigen Tests for the Primary Diagnosis of Helicobacter pylori Infection in Turkish Patients with Dyspepsia

“…The latter was based on a mix of monoclonal antibodies that might ensure greater reproducibility of the test results. Preliminary results of this test have been excellent [13–16].…”

“…This test is based on the use of polyclonal antibodies and intertest variability has been found which was attributed to the different antigenic compositions of the test series used [12]. After this, a new enzyme immunoassay for detecting H. pylori antigens in stools that was based on a mix of monoclonal antibodies (FemtoLab H. pylori, Connex, Martinsried, Germany) was put on the market and preliminary results have been excellent [13][14][15][16].…”

Stool antigen assay (HpSA) is less reliable than urea breath test for post‐treatment diagnosis of Helicobacter pylori infection

“…Although some investigators have demonstrated that UBT and HpSA are absolutely equivalent in terms of sensitivity and specificity in the evaluation of eradication therapy, 15,23,24 others have documented a lower than expected reliability of HpSA in this setting. [25][26][27][28][29] It has been rightly emphasized that many studies on the performance of HpSA in post-treatment assessment have used UBT as the gold standard, and this has certainly diminished the meaning of the results. 30,31 However, the few studies using biopsy-based methods as the gold standard have provided conflicting results.…”

Stool antigen for the diagnosis of Helicobacter pylori infection in cirrhosis: comparative usefulness of three different methods

“…13 In contrast, the 13 C-urea breath test is very sensitive and specific, but expensive, as it usually requires trained personnel to obtain the breath samples, and both 13 C-urea and the instrumentation necessary to interpret the samples are costly. 14 [15][16][17][18] However, these new stool antigen diagnostic tests have not been evaluated in patients with cirrhosis. Therefore, the objective of this study was to evaluate the reliability of these new stool antigen detection tests for the diagnosis of H. pylori infection in cirrhosis.…”

“…Excellent results have been reported with all these tests in dyspeptic patients. [15][16][17][18] However, these new stool antigen diagnostic tests have not been evaluated in patients with cirrhosis. Therefore, the objective of this study was to evaluate the reliability of these new stool antigen detection tests for the diagnosis of H. pylori infection in cirrhosis.…”