Diagnosis of genital cervical schistosomiasis: comparison of cytological, histopathological and parasitological examination.

Abstract

Abstract. Granulomatous inflammation of the cervix uteri is a common manifestation of infection with Schistosoma haematobium. In women the cervix is the most common site of infection by S. haematobium. Three methods were used to assess the performance of three different ways of detecting schistosome eggs in cervical tissue: cytological examination of a cervical smear, histological examination of a cervical biopsy, and direct examination of cervical tissue obtained by forceps biopsy (quantitative compressed biopsy technique [QCBT]). Of 228 women studied who lived in an S. haematobium endemic area in Tanzania, 112 (49%) had schistosome eggs detected in the cervix using QCBT. Histological examination detected eggs in 40 of 228 (18%). The cytological examination of cervical smears yielded only 6 positive results (3%). The median egg load in the cervical tissue of cases correctly diagnosed by histology was significantly higher than the egg load in the misclassified cases, indicating that the sensitivity of histological sectioning increases with egg density. We conclude that the QCBT is the diagnostic test of choice for schistosomiasis of the genital cervix.

Cervical schistosomiasis infection in a woman with an abnormal smear

“…Cytological examination of a cervical smear has been used, but appears to be a poor diagnostic tool. 11 This may explain why the diagnosis was missed on two cervical smears in this case.…”

Esquistossomose endocervical

“…Clinicamente, o acometimento do trato genital feminino pelo esquistosomo geralmente é assintomático, e os ovos são descobertos em exames rotineiros 6 . Entretanto, podem ocorrer sangramentos pós-coital, intermenstrual e pós-menstrual, infertilidade, corrimento vaginal e dismenorréia.…”

“…Ao exame colposcópico, o colo pode exibir hipertrofia nodular, lesões polipóides, úlceras, erosões e lesões de aspecto arenoso 6 . O diagnóstico pode ser feito através da pesquisa de ovos em esfregaços vaginais rotineiros ou através do exame histológico feito em amostras provenientes de biópsia 1 .…”

Cervical Schistosomiasis as a Risk Factor of Cervical Uterine Dysplasia in a Traveler

“…Diagnosis of CS is relatively easy using the quantitative compressed biopsy technique. 5 CS is a curable disease. Indeed, after a single dose of praziquantel, lesions usually resolved within 9 weeks.…”