2013
DOI: 10.1007/s12262-013-0826-3
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Diagnosis of Gallbladder Perforation—a Puzzle!

Abstract: Gallstone disease is common and complications frequently encountered include acute cholecystitis, acute pancreatitis, and cholangitis, but gallbladder perforation (GBP) is rare. A definitive diagnosis is uncommon before surgery and morbidity and mortality associated with this condition are high. Reported incidence ranges between 2 and 10.6 % in patients with acute cholecystitis but is higher in patients managed conservatively. We report here five patients with GBP to show the difficulty in making an early diag… Show more

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Cited by 7 publications
(13 citation statements)
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“…Our study included with mean age 60 years, 57.8% were either known to be diabetic, and this agrees with Morris et al that found it common in diabetic and cardiac patients and elderly patients are especially susceptible to GBP [1]. Acute uncomplicated cholecystitis is more common in females, but GBP is more common in males [8]. However, in this study, a higher incidence of GBP was observed in females (males to females = 8:11).…”
Section: Discussionsupporting
confidence: 90%
“…Our study included with mean age 60 years, 57.8% were either known to be diabetic, and this agrees with Morris et al that found it common in diabetic and cardiac patients and elderly patients are especially susceptible to GBP [1]. Acute uncomplicated cholecystitis is more common in females, but GBP is more common in males [8]. However, in this study, a higher incidence of GBP was observed in females (males to females = 8:11).…”
Section: Discussionsupporting
confidence: 90%
“…Nonetheless, the demonstration of the fundus is of paramount importance. As shown here, and by others [3,4,14,15], most GB perforations involve this area. The propensity of the fundus to perforate is related mainly to a relatively poor blood supply [3,15].…”
Section: Accepted Manuscriptsupporting
confidence: 85%
“…formation of the abscess can be detected early using abdominal US. 5,6 In unclear or difficult cases, such as ours, an abdominal CT scan can provide more detailed information. 6 In most cases of gallbladder perforation the optimal treatment option is cholecystectomy.…”
Section: Discussionmentioning
confidence: 97%
“…5,6 In unclear or difficult cases, such as ours, an abdominal CT scan can provide more detailed information. 6 In most cases of gallbladder perforation the optimal treatment option is cholecystectomy. However, if a patient is at high surgical risk, placement of a percutaneous, transhepatic drainage tube combined with the administration of antibiotics may provide definitive therapy.…”
Section: Discussionmentioning
confidence: 97%