Diagnosis of Deep-Vein Thrombosis Using Duplex Ultrasound

White, Richard; McGahan, John P.; Daschbach, Martha M.; Hartling, R. P.

doi:10.7326/0003-4819-111-4-297

Cited by 267 publications

(77 citation statements)

References 40 publications

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“…Although contrast venography has been considered as the gold standard for the diagnosis of DVT (4), it is invasive and requires contrast media. Presently, duplex and compression ultrasonography is the preferred technique to image flow in the proximal veins of the lower leg (5). It combines morphological (e.g., thrombus) and functional aspects (e.g., venous flow) with a functional stress test such as gentle pressure on the veins (i.e., compression).…”

Section: Introductionmentioning

confidence: 99%

Real-time magnetic resonance imaging of deep venous flow during muscular exercise—preliminary experience

Joseph

Merboldt

Voit

et al. 2016

Cardiovasc. Diagn. Ther.

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Background: The accurate assessment of peripheral venous flow is important for the early diagnosis and treatment of disorders such as deep-vein thrombosis (DVT) which is a major cause of post-thrombotic syndrome or even death due to pulmonary embolism. The aim of this work is to quantitatively determine blood flow in deep veins during rest and muscular exercise using a novel real-time magnetic resonance imaging (MRI) method for velocity-encoded phase-contrast (PC) MRI at high spatiotemporal resolution.

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Section: Introductionmentioning

confidence: 99%

Real-time magnetic resonance imaging of deep venous flow during muscular exercise—preliminary experience

Joseph

Merboldt

Voit

et al. 2016

Cardiovasc. Diagn. Ther.

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show abstract

“…The overall sensitivity is 93% (range 87-100%) and the overall specificity is 94% (range 78-100%) [94][95][96][97][98], In a recent study it was shown that US and duplex are methods with comparable high accuracy. Because of its availability, accu racy, cost-effectiveness and simplicity US was rec ommended as the primary diagnostic test [99].…”

Section: (Colour) Duplex Scanningmentioning

confidence: 97%

Diagnosis of deep vein thrombosis, an overview

Janssen

Wollersheim

Nováková

et al. 1996

The Netherlands Journal of Medicine

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A bstractBecause clinical signs and symptoms are unreliable the diagnosis of deep vein thrombosis (DVT) should be objectified. Advantages and disadvantages of contrast venography, plethysmography, ultrasound techniques, fibrino gen leg scanning, computer-assisted tomography, magnetic resonance imaging and blood tests are discussed. In patients with a first event of suspected DVT non-invasive methods like serial plethysmography or ultrasound testing are sensitive and specific enough to make a treatment decision. It is safe to withhold anticoagulants if the test remains normal within 1 week. In patients with suspected recurrent DVT new non-invasive techniques are being tested, but up to now the definitive objective diagnostic test continues to be contrast venography. In first period as well as in recurrent DVT D-Dimer testing could be an additional test to exclude active thromboembolism.

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“…Although the D-dimer assay has a high negative predictive value (96-100%), which allows exclusion of VTE [3][4][5], its specificity is only 36-44% [15,16]. On the other hand, lower extremity venous ultrasonography has high sensitivity (93-96%) as well as high specificity (98-99%) for the diagnosis of DVT [6][7][8]. However, ultrasonography in all preoperative patients as a screening tool is considered to represent overuse of this diagnostic resource [17,18].…”

Section: Discussionmentioning

confidence: 99%

“…The D-dimer assay is a safe and useful tool with a high sensitivity (97-100%) for excluding DVT and a high negative predictive value (96-100%) [3][4][5]. Lower extremity venous ultrasonography is the standard method for the diagnosis of DVT, with a high sensitivity (93-96%) and high specificity (98-99%) [6][7][8]. In July 2012, we started preoperative DVT screening at our institution using a combination of D-dimer measurements and lower extremity venous ultrasonography in patients undergoing gastric cancer surgery.…”

Section: Introductionmentioning

confidence: 99%

Incidence of and risk factors for preoperative deep venous thrombosis in patients undergoing gastric cancer surgery

et al. 2017

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Background Pulmonary thromboembolism (PE) is one of the life-threatening complications of gastric cancer surgery. D-dimer assay is a safe and rapid tool to exclude the presence of deep venous thrombosis (DVT). In July 2012, we started preoperative DVT screening of patients scheduled for gastric cancer surgery using a combination of D-dimer measurements and lower extremity venous ultrasonography to prevent PE. Methods Between July 2012 and August 2015, 976 consecutive patients underwent gastric cancer surgery with preoperative D-dimer screening. Lower extremity venous ultrasonography was performed in patients with a positive D-dimer assay result (greater than 1.0 lg/ml). The incidence of and risk factors for preoperative DVT and the incidence of PE were examined in patients undergoing gastric cancer surgery. Results Of the 976 patients, 176 (18.0%) showed positive D-dimer assay results, and in 13 (1.3%) DVT was diagnosed by lower extremity ultrasonography. Our analysis identified neoadjuvant chemotherapy as a risk factor for preoperative detection of DVT in patients undergoing gastric cancer surgery (P = 0.021). The incidence of PE was 0.1% (1/976). Conclusion Preoperative gastric cancer patients receiving neoadjuvant chemotherapy seem to be at higher risk for the development of DVT.

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Diagnosis of Deep-Vein Thrombosis Using Duplex Ultrasound

Abstract: Duplex ultrasound appears to be very accurate in the detection of acute proximal deep-vein thrombosis. This test has major advantages as well as certain limitations compared with other diagnostic methods.

Cited by 267 publications

References 40 publications

Real-time magnetic resonance imaging of deep venous flow during muscular exercise—preliminary experience

Real-time magnetic resonance imaging of deep venous flow during muscular exercise—preliminary experience

Diagnosis of deep vein thrombosis, an overview

Incidence of and risk factors for preoperative deep venous thrombosis in patients undergoing gastric cancer surgery

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