Diagnosis of conjunctival B-cell lymphoma by polymerase chain reaction heteroduplex analysis

Strauss, Erich C.; Warren, John F; Margolis, Todd P.; Holsclaw, Douglas S.

doi:10.1016/s0002-9394(03)00081-3

Cited by 10 publications

(5 citation statements)

References 5 publications

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“…Giant papillae can be mis-diagnosed as conjunctival lymphoma. 6,7 Conjunctival tumour should be ruled out if the condition is unresponsive to anti-allergic drugs and papillae are relatively large. As the result of incisional biopsy was negative, allergic conjunctivitis was approved as the diagnosis.…”

Section: Discussionmentioning

confidence: 99%

A rare case of asymmetrical vernal keratoconjunctivitis

Pawaiya¹,

Arora²,

Chawala³

et al. 2020

SUJHS

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A 12 years old boy presented in our OPD complaints of itching and redness in right eye since 2 months. There was associated history of copious mucous discharge in both eyes. On slit-lamp bio microscopic examination, right eye revealed two giant cobblestone papillae along with multiple small papillae while in the left eye small papillae were present. Right eye also showed Punctuate epithelial keratitis with no signs of corneal involvement in left eye. There was no history of use of contact lenses of suturing to the eye, hence, deviating from the diagnosis of giant papillary conjunctivitis. He was treated with oral and topical anti allergic medications. Cobblestone papillae persisted even after maximal tolerated dose. Two doses of Supratarsal injection of 20 mg Triamcenolone Acetonide (Corticosteroid) were given in right eye one month apart. We observed complete recovery from allergic symptoms. Cobblestone papillae and punctuate epithelial erosions regressed completely. Patient was asymptomatic after two months, i.e. no recurrence. In this case, we indicate the use of Supratarsal corticosteroid injection in recalcitrant vernal kerato-conjunctivitis. Promising results were seen without adjuvant topical or oral medications.

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Section: Discussionmentioning

confidence: 99%

A rare case of asymmetrical vernal keratoconjunctivitis

Pawaiya¹,

Arora²,

Chawala³

et al. 2020

SUJHS

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“…Conjunctival lymphomas can masquerade as chronic conjunctivitis that does not respond to various treatments [ 15 ]. Strauss et al reported a 32-year-old man who presented with follicular-like palpebral conjunctivitis with unilateral blepharoptosis that proved to be a B-cell lymphoma [ 12 ]. Shields et al reported a series of 117 cases of conjunctival lymphoid tumors.…”

Section: Discussionmentioning

confidence: 99%

“…It does occur in young adult or children [ 9 – 11 ]. “Salmon patch” is the typical clinical presentation of conjunctival lymphoma, and, unlike orbital lymphoma, such conjunctival lesions rarely present as blepharoptosis [ 2 , 12 ]. Here we report a case of conjunctival lymphoma in a young woman complicated by pregnancy.…”

Section: Introductionmentioning

confidence: 99%

Conjunctival lymphoma during pregnancy: a case report

2017

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BackgroundTo present a case of conjunctival lymphoma in a young woman complicated by pregnancy.Case presentationA 38-year-old previously healthy woman presented with a 2-year history of progressive right blepharoptosis. Giant papillomatous sessile masses were identified in the upper and lower fornix bilaterally and involved the tarsus of the right upper lid. The remaining ophthalmic examination was unremarkable. Histopathology and immunohistochemistry showed mucosa-associated lymphoid tissue (MALT) lymphoma with immunoglobulin kappa monotype. Further workup showed no evidence of systemic lymphoma or orbital involvement.ConclusionsPartial regrowth of conjunctival lymphoma occurred 6 months after excision and the MALT lymphoma remained indolent during the course of her pregnancy without radiotherapy.

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“…Strauss et al reported a young male contact lens wearer who presented with giant papillary conjunctivitis of the upper lid with associated blepharoptosis. 10 The development of ptosis necessitated a biopsy and polymerase chain reaction analysis, which revealed a low-grade B-cell lymphoma. To the best of our knowledge, our report is the first in the English literature involving this unique presentation of bilateral conjunctival FL presenting solely as chronic follicular conjunctivitis, without a mass or other suspicious lesion.…”

Section: Discussionmentioning

confidence: 99%

Follicular Lymphoma Presenting Solely as Chronic Follicular Conjunctivitis

Duncan¹,

Chen²,

Fuchs³

et al. 2016

Cornea

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Purpose: Conjunctival lymphoma rarely can have atypical clinical presentations. The authors report a case of conjunctival follicular lymphoma that presented solely as bilateral chronic follicular conjunctivitis. This case underscores that the pathological characteristics of conjunctival follicles can only be determined by histopathologic examination.Methods: The patient underwent conjunctival scraping and biopsy after clinical history and examination failed to reveal the etiology of his chronic, symptomatic, follicular conjunctivitis.

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Diagnosis of conjunctival B-cell lymphoma by polymerase chain reaction heteroduplex analysis

Cited by 10 publications

References 5 publications

A rare case of asymmetrical vernal keratoconjunctivitis

A rare case of asymmetrical vernal keratoconjunctivitis

Conjunctival lymphoma during pregnancy: a case report

Follicular Lymphoma Presenting Solely as Chronic Follicular Conjunctivitis

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