Diagnosis of Chlamydia trachomatis Infection

Visser, A T; Hoosen, Anwar A.

doi:10.5772/38804

Cited by 1 publication

(2 citation statements)

References 115 publications

(86 reference statements)

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“…Sensitivity in experienced laboratory approaches 85% compared with NAATs [ 145 ]. Another disadvantage of this method is that it requires perfectly organized cold chain of transportation in order to deliver viable microorganism to the laboratory [ 146 ]. However, because an isolation of living microorganism is the definitive method for the diagnosis, culture remains the method of choice in terms of medicolegal investigations and follow-up after completed therapy [ 145 ].…”

Section: Laboratory Diagnosismentioning

confidence: 99%

“…Those tests do not require stringent conditions for specimen transportation. The DFA test is the only diagnostic test that permits simultaneous assessment of specimen adequacy by visualization of epithelial cells present in the smear [ 146 ]. In relation to culture, the sensitivity and specificity of DFA tests that use antibodies to MOMP are 80–90% and 98-99%, respectively [ 153 ].…”

Section: Laboratory Diagnosismentioning

confidence: 99%

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Chlamydia trachomatisand Genital Mycoplasmas: Pathogens with an Impact on Human Reproductive Health

Ljubin‐Sternak

Meštrović²

2014

Journal of Pathogens

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The most prevalent, curable sexually important diseases are those caused by Chlamydia trachomatis (C. trachomatis) and genital mycoplasmas. An important characteristic of these infections is their ability to cause long-term sequels in upper genital tract, thus potentially affecting the reproductive health in both sexes. Pelvic inflammatory disease (PID), tubal factor infertility (TFI), and ectopic pregnancy (EP) are well documented complications of C. trachomatis infection in women. The role of genital mycoplasmas in development of PID, TFI, and EP requires further evaluation, but growing evidence supports a significant role for these in the pathogenesis of chorioamnionitis, premature membrane rupture, and preterm labor in pregnant woman. Both C. trachomatis and genital mycoplasmas can affect the quality of sperm and possibly influence the fertility of men. For the purpose of this paper, basic, epidemiologic, clinical, therapeutic, and public health issue of these infections were reviewed and discussed, focusing on their impact on human reproductive health.

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Section: Laboratory Diagnosismentioning

confidence: 99%

Section: Laboratory Diagnosismentioning

confidence: 99%