Diagnosis of Cancer

Alelyani, Fayez; Seday, Anas Abdulhamid; Al-Toub, Mashael; Alwatban, Adnan

doi:10.2174/9789815124606123010005

Cited by 2 publications

(2 citation statements)

References 77 publications

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“…In adult oncology, Alelyani et al. reviewed the routes to diagnosis in adult cancer patients and found that self‐examination and screening procedures are only helpful in cancers that are visible, whereas others are discovered after disease progression due to symptoms 25 . Screening programs as in adults are not useful in children as most of their cancers are not visible at early stages.…”

Section: Discussionmentioning

confidence: 99%

The impact of the route to diagnosis in nephroblastoma

Mergen,

Welter,

Furtwängler

et al. 2024

Cancer Medicine

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IntroductionWilms tumor (WT) is the most common childhood kidney cancer. It is a rapid growing embryonal tumor in young children and can be diagnosed with and without tumor related symptoms.MethodsWe retrospectively analyzed the route to diagnosis of WT treated prospectively according to the SIOP 93‐01/GPOH and 2001/GPOH in Germany between 1993 and 2022. Four routes were defined: diagnosis due to tumor‐related symptoms, incidental diagnosis during another disease, diagnosis by preventive examinations, and diagnosis within a surveillance program. For these groups we compared clinical and tumor characteristics and outcome.ResultsOf 2549 patients with WT 1822 (71.5%) were diagnosed by tumor‐related symptoms, 472 (18.5%) incidentally, 213 (8.4%) by preventive medical examinations, and 42 (1.6%) by surveillance. Age, general health status, tumor volume, and local and overall stage varied significantly between these groups. The youngest patients were those diagnosed by preventive medical examination (mean: 1.70 years). These patients also showed the best general health status. Tumor volume at diagnosis (549 mL) and after preoperative chemotherapy (255 mL) was significantly higher for children with tumor‐related symptoms. The highest percentage of local stage I (78.6%) and the lowest percentage of metastatic disease (4.8%) was found in the surveillance group. The outcome of patients was not significantly different, with up to 19.0% relapses in the surveillance group and 3.0% deaths in the group with tumor‐related symptoms.ConclusionThe route to diagnosis of WT correlates with age, general health status, tumor volume, and stage distribution, but does not impact the outcome of patients. Nonetheless, diagnosis without tumor related symptoms results in lower treatment burden and thus improved quality of life.

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Section: Discussionmentioning

confidence: 99%

The impact of the route to diagnosis in nephroblastoma

Mergen,

Welter,

Furtwängler

et al. 2024

Cancer Medicine

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“…The diagnosis of an oncological disease and hospitalization, whether it is day or continuous hospitalization, are often very critical moments for patients and their families (Rebegea et al, 2018, Paduraru et al, 2019. The diagnosis of cancer represents a stressful event for the individual (Ciuhu et al, 2015), which requires a major adaptation effort, generates an upheaval in daily life -due to the treatments and their side effects -and an important psychological crisis resulting from the unknown evolution of the disease and the threat it represents for the patient's future and life (Alelyani et al, 2023).…”

Section: Introductionmentioning

confidence: 99%

The Integration of Psychological Intervention in the Multimodal Treatment of Patients with Prostate Cancer and Erectile Dysfunction

Valcu,

Firescu,

Constantin

et al. 2024

BRAIN

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Male sexual dysfunction refers to a lack of attraction and a lack of normal sexual performance. The most common sexual dysfunction in men is erectile dysfunction. Erectile dysfunction is the inability to achieve an erection or to sustain satisfactory sexual intercourse. Sexual dysfunction is associated with oncological treatment, having a significant impact on the quality of life. Sexuality is a frantic sense of awakening to life, it is excitement and a lot of energy, it gives the feeling of invincibility, it is the opposite of death. For many cancer patients, getting an erection is a negative problematic experience, combined with feelings of hopelessness, depression, accompanied by loss of self-esteem. Taking into account the medical aspect, the present paper highlights the interpersonal psychological aspect with reference to the cognitive-behavioural model. The present analysis describes the problem of sexual dysfunction and illustrates a panorama of therapeutic models to plan an effective intervention. This study aims to perform a review of the evidence on the role of cognitive-behavioural psychotherapy in addressing erectile dysfunction problems in prostate cancer patients. An extensive bibliographic search of online database and relevant manuscripts was followed.

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Diagnosis of Cancer

Cited by 2 publications

References 77 publications

The impact of the route to diagnosis in nephroblastoma

The impact of the route to diagnosis in nephroblastoma

The Integration of Psychological Intervention in the Multimodal Treatment of Patients with Prostate Cancer and Erectile Dysfunction

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