Diagnosis of brain abscess by magnetic resonance spectroscopy

Martínez-Pérez, Irene; Moreno, Àngel; Alonso, Juli; Aguas, Jesús; Conesa, Gerard; Capdevila, Antoni; Arús, Carles

doi:10.3171/jns.1997.86.4.0708

Cited by 47 publications

(32 citation statements)

References 21 publications

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“…However, the mean spectra showed a broad hump around the region 3.2-3.6 ppm, which is not seen in any of the other mean spectra. Six out of the eight abscesses had a negative signal at 0.97 ppm which is most likely from the coupled spin signals of amino acids (34). The other groups were too small or variable to draw any clear conclusions from the visual inspection of spectra.…”

Section: Spectral Analysismentioning

confidence: 99%

Development of a decision support system for diagnosis and grading of brain tumours using in vivo magnetic resonance single voxel spectra

et al. 2006

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A computer-based decision support system to assist radiologists in diagnosing and grading brain tumours has been developed by the multi-centre INTERPRET project. Spectra from a database of 1 H single-voxel spectra of different types of brain tumours, acquired in vivo from 334 patients at four different centres, are clustered according to their pathology, using automated pattern recognition techniques and the results are presented as a two-dimensional scatterplot using an intuitive graphical user interface (GUI). Formal quality control procedures were performed to standardize the performance of the instruments and check each spectrum, and teams of expert neuroradiologists, neurosurgeons, neurologists and neuropathologists clinically validated each case. The prototype decision support system (DSS) successfully classified 89% of the cases in an independent test set of 91 cases of the most frequent tumour types (meningiomas, low-grade gliomas and high-grade malignant tumours-glioblastomas and metastases). It also helps to resolve diagnostic difficulty in borderline cases. When the prototype was tested by radiologists and other clinicians it was favourably received. Results of the preliminary clinical analysis of the added value of using the DSS for brain tumour diagnosis with MRS showed a small but significant improvement over MRI used alone. In the comparison of individual pathologies, PNETs were significantly better diagnosed with the DSS than with MRI alone.

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Section: Spectral Analysismentioning

confidence: 99%

Development of a decision support system for diagnosis and grading of brain tumours using in vivo magnetic resonance single voxel spectra

et al. 2006

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“…The information provided can, as illustrated in Fig. 3, be used for differential diagnosis of focal vs. infiltrating tumors and ring-enhancing tumors vs. abscesses (55,56).…”

Section: Cerebral Space-occupying Lesionsmentioning

confidence: 99%

Proton MR spectroscopy in clinical routine

Burtscher

Holtås

2001

Magnetic Resonance Imaging

114

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“…However, rapid and correct diagnosis is needed because these different entities require different types of treatment. Proton magnetic resonance spectroscopy ( 1 H-MRS) 3,4,7,8) or diffusion-weighted MR imaging (DWI) 1,2,5,6,9) have been used for the diagnosis of cystic lesions, but not in combination. We describe two cases illustrating the use of 1 H-MRS and DWI for the differential diagnosis of brain abscess and necrotic tumor.…”

Section: Introductionmentioning

confidence: 99%

Brain Abscess and Glioblastoma Identified by Combined Proton Magnetic Resonance Spectroscopy and Diffusion-Weighted Magnetic Resonance Imaging. Two Case Reports.

Nakaiso

Uno

Harada

et al. 2002

Neurol. Med. Chir.(Tokyo)

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The differential diagnosis between brain abscesses and necrotic tumors such as glioblastomas is sometimes difficult to establish by conventional computed tomography and magnetic resonance imaging. Combined proton magnetic resonance spectroscopy ( 1 H-MRS) and diffusion-weighted magnetic resonance imaging (DWI) were used to establish the preoperative diagnosis of brain abscess and glioblastoma. DWI visualized the brain abscess as a homogeneous hyperintense lesion and 1 H-MRS revealed the presence of acetate, lactate, and amino acids and the absence of the normal brain components. DWI sometimes shows glioblastoma as a hyperintense lesion, but 1 H-MRS reveals markedly increased lactate and decreased N-acetyl-aspartate. Combined DWI and 1 H-MRS findings can distinguish brain abscess and glioblastoma.

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Diagnosis of brain abscess by magnetic resonance spectroscopy

Cited by 47 publications

References 21 publications

Development of a decision support system for diagnosis and grading of brain tumours using in vivo magnetic resonance single voxel spectra

Development of a decision support system for diagnosis and grading of brain tumours using in vivo magnetic resonance single voxel spectra

Proton MR spectroscopy in clinical routine

Brain Abscess and Glioblastoma Identified by Combined Proton Magnetic Resonance Spectroscopy and Diffusion-Weighted Magnetic Resonance Imaging. Two Case Reports.

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