Diagnosis of acute intoxications in critically ill patients: focus on biomarkers – part 2: markers for specific intoxications

Reisinger, Alexander Christian; Rabensteiner, Jasmin; Hackl, Gerald

doi:10.1080/1354750x.2020.1725787

Cited by 3 publications

(1 citation statement)

References 179 publications

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“…Taxine A and B are volatile and difficult to detect. Therefore, paclitaxel can be used as a specific biomarker for yew poisoning in primary high performance liquid chromatography with mass spectrometry (HPLC-MS) screening, when patient history and gastroscopy are inconclusive [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Cardiogenic shock due to yew poisoning rescued by VA-ECMO: case report and literature review

et al. 2022

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Ingestion of leaves of the European yew tree ( Taxus baccata ) can result in fatal cardiac arrhythmias and acute cardiogenic shock. This cardiotoxicity derives from taxine alkaloids that block cardiac voltage-gated sodium and calcium channels. Prompt initiation of venoarterial extracorporeal membrane oxygenation is essential to bridge these critically ill patients to recovery, as there is no antidote available. We here report a 39-year old patient with toxic cardiogenic shock after yew poisoning, who was successfully rescued by venoarterial extracorporeal membrane oxygenation and had a full neurological recovery. This report emphasizes the role of intoxications as reversible causes of cardiac arrest and adds further evidence to the body of existing literature thus encouraging the early use of venoarterial extracorporeal membrane oxygenation in patients with yew poisoning and cardiogenic shock.

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Section: Discussionmentioning

confidence: 99%