Diagnosis of acute bone/bone marrow infarction of the mandible in sickle hemoglobinopathy

Jaw Osteomyelitis as a Complication of Sickle Cell Anaemia in Three Omani Patients: Case reports and literature review

“…Patients with SCJO may present with dental pain, pus discharge, necrosis or numbness in the perioral region, the latter of which is predominantly located in the lower lip in cases of inferior alveolar nerve involvement. 17,18 In the present case report, the two patients with mandibular osteomyelitis presented with pus discharge in the molar region and were initially diagnosed with pericoronitis. Olaitan et al and Shroyer et al also reported pericoronitis to be a common cause of osteomyelitis among SCA patients with mandibular osteomyelitis.…”

Correlation between maxillofacial radiographic features and systemic severity as sickle cell disease severity predictor

“…Radiopacities in the bone are reported in SCD patients, occurring more commonly in posterior mandible along vascular canals or apical region of teeth, and reflect a previous history of bone infarcts [21]. During generalized sickle cell crises, vaso-occlusive involvement of mandible of ischemic and aseptic nature can occur, displaying odontogenic pain or neuropathy [17,29] and contributing for dental pulp death [36]. Literature reports few cases of mandibular infarction [14,15,17,37], probably due to significant collateral circulation and difficulty in documenting infarction in this bone [9].…”

“…During generalized sickle cell crises, vaso-occlusive involvement of mandible of ischemic and aseptic nature can occur, displaying odontogenic pain or neuropathy [17,29] and contributing for dental pulp death [36]. Literature reports few cases of mandibular infarction [14,15,17,37], probably due to significant collateral circulation and difficulty in documenting infarction in this bone [9]. Kavadia-Tsatala et al [29] found 14% of 42 SCA patients with radiopaque areas on panoramic radiographs that were considered of vasoocclusive origin considering symptomatology and absence of dental lesions or acute infection.…”

“…Considering the maxillofacial area, radiographic features frequently associated with SCD patients have been reported, such as increase radiolucency of the jaws due to the decreased number of trabeculae, coarse trabeculae pattern, thin inferior border of mandible, distinct areas of radiopacity, stepladder appearance created in the interdental alveolar bone by horizontal rows of trabeculation and osteomyelitis [4,[14][15][16][17][18][19][20][21][22]. Few studies have analyzed their prevalence among SCD patient and healthy controls [23][24][25][26][27][28][29][30].…”

Pseudo-kyste anévrysmal mandibulaire associé à l’anémie falciforme

“…Les signes et symptômes cliniques les plus fré-quents observés dans cette maladie sont l'asthénie, une dyspnée à l'effort, une tachycardie, des troubles rétiniens, une susceptibilité accrue aux infections, des ulcères cutanés sur les membres inférieurs, ainsi qu'un retard du croissance [1,3] . Les phénomènes micro-emboliques ou vaso-occlusifs sont responsables de crises douloureuses aiguës dont la durée varie de quelques heures à quelques semaines.…”