Diagnosis and Treatment of Urinary Tract Infections

Lang, Gordon R.; Levin, Stuart

doi:10.1016/s0025-7125(16)32447-6

Cited by 6 publications

(1 citation statement)

References 90 publications

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“…Several investigators (21,22,33) have stressed the necessity of urography or even a complete urological examination of women whose first verified UTI is not cured or recurs. Under these circumstances, a total of 37 of our subjects (3% of all the women aged 40-64) would have needed further examinations ( I 1 remained uncured, UTI recurred in 23, and 3 already had a nitrofurantoinresistant bacterial strain as a result of recurring UTIs).…”

Section: Discussionmentioning

confidence: 99%

Screening for and Treatment of Bacteriuria in a Middle‐aged Female Population

Takala

Jousimies

Sievers

1977

Journal of Internal Medicine

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Forty‐seven of the 55 subjects with bacteriuria found during a screening of an unselected female population aged 40–64 years (1312 women, 93.2% of whom were examined) have been treated with a systematic 2‐week nitrofurantoin therapy and 77% of them were cured. During a 1‐year follow‐up, urinary tract infection (UTI) recurred in 68% of those cured; thus only 24% of those treated had been cured and remained uninfected for a year. Although the result of treatment in the group with no diabetes, hypertension or chronic rheumatoid arthritis was better (88%) than in the group with these diseases (46%), the cured subjects in both groups had a similar frequency of recurrences. A previous UTI did not appear to have a negative effect on the result of treatment, neither did it increase the number of recurrent UTIs. The fact that even in the group with no complicating diseases only 28% of those treated were cured and remained free from bacteriuria for 1 year proves that, so far, no satisfactory therapy is available for mass use in the treatment of bacteriuria following a systematic screening of middle‐aged nonpregnant women. In addition to the lack of therapeutic methods, the systematic screening for bacteriuria in middle‐aged women was found to suffer from limited resources for further diagnostic examinations: according to the present study, a total of 3% of middle‐aged women need further examinations following the screening for and treatment of bacteriuria.

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Section: Discussionmentioning

confidence: 99%

Screening for and Treatment of Bacteriuria in a Middle‐aged Female Population

Takala

Jousimies

Sievers

1977

Journal of Internal Medicine

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Detection of Bacteriuria in Pediatric Outpatients

Marr¹

1975

Am J Dis Child

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\s=b\Urine samples from 1,003 pediatric patients were examined for bacteriuria with a culture-nitrite strip test, along with microscopic assessment of pyuria and conventional chemical analysis. The latter two methods proved of little value in reliably detecting or excluding substantial bacteriuria. An overall prevalence of 5.2% was shown.Using Microstix Reagent Strips, 92 urine samples with substantial colony counts were detected. Subculture from the strips disclosed that 52 of these involved single pathogens, interpreted as true bacteriuria. When Microstix growth results were compared with the calibrated loop method on 108 randomly selected specimens, the strip gave only two false negatives and one false positive. Bacteriuria screening should be done in high-risk groups and in asymptomatic children as part of the health evaluation. The index of suspicion should be higher in girls, and reliable interpretation of culture results requires attention to proper specimen collection.(Am J Dis Child 129: [940][941][942][943] 1975) The urinary tract is often the focus of infection in the febrile child. Even without specific localizing signs, the normal laboratory and clin-

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