Diagnosis and treatment of refractory infectious diseases using nanopore sequencing technology: Three case reports
Qing-Mei Deng,
Jian Zhang,
Yi-Yong Zhang
et al.
Abstract:BACKGROUND
Infectious diseases are still one of the greatest threats to human health, and the etiology of 20% of cases of clinical fever is unknown; therefore, rapid identification of pathogens is highly important. Traditional culture methods are only able to detect a limited number of pathogens and are time-consuming; serologic detection has window periods, false-positive and false-negative problems; and nucleic acid molecular detection methods can detect several known pathogens only once. Three-gen… Show more
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