Diagnosis and treatment of primary paracoccidioidomycosis in oral mucosa

Tomo, Saygo; Silva, Renan Lemos da; Miyahara, Glauco Issamu; Stefanini, Aline Reis; Simonato, Luciana Estevam

doi:10.1111/dth.13314

Cited by 2 publications

(2 citation statements)

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“…25 . Population studies that follow the therapeutic evolution of patients affected by fungal infections report a higher rate of treatment dropout during follow-up precisely in the first four months, leading to the belief that patient adherence to long-term treatments for diseases with a chronic infectious profile is a challenge for clinical practice since the act of using prescribed medications and monitoring the therapeutic evolution consist of a behavioral profile that depends exclusively on the patient 20,17,27,28 The literature has reinforced the need for surveillance and mandatory notification for paracoccidioidomycosis; actions capable of promoting environmental changes tend to facilitate contact with the etiological agent. Correct monitoring and geographic location of new cases would incur in reducing the relative risks of human intervention in order to reduce and perhaps prevent future episodes of paracoccidioidomycosis infection 3,11,29 .…”

Section: Andrade Et Al 2019mentioning

confidence: 99%

diagnostic challenge in an individual with Paracoccidioidomycosis during hospitalization in times of COVID-19

Baldo

Raffaele²,

Santos³

et al. 2022

Int J Innov Educ Res

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Paracoccidioidomycosis (PCM) is a deep fungal infection, endemic with considerable morbidity in South America, whose first symptoms can occur in the oral cavity. A 47-year-old male patient, leucoderma, living on the streets, presenting dyspnea, pain during the speech, and dysphagia, was referred for admission to the ICU for suspected COVID-19 infection. The intensive care physician's evaluation revealed a tongue lesion with suspected carcinoma. By dentist investigation, was observed the presence of moriform lesions with high borders delimitation in the tongue. Also, granulomatous ulcers with irregular texture, suggesting moriform stomatitis, the chest tomography revealed diffuse thickening of the bronchial walls, indicating chronic bronchopathy with discrete centrilobular nodules, sometimes confluent. Incisional tongue biopsy associated with lung imaging confirmed the diagnosis of PCM, and the patient was referred to the referral center for the treatment of fungal diseases. The involvement of the oral environment as a region to the appearance of detectable first symptoms of PCM suggests the need for the oral evaluation by a specialist as a diagnostic tool.

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Section: Andrade Et Al 2019mentioning

confidence: 99%

diagnostic challenge in an individual with Paracoccidioidomycosis during hospitalization in times of COVID-19

Baldo

Raffaele²,

Santos³

et al. 2022

Int J Innov Educ Res

View full text Add to dashboard Cite

show abstract

“…Paracoccidioidomycosis is a subcutaneous fungal infection caused by a dimorphic fungus Paracoccidioides brasiliensis . [ 1 ] It is primarily a systemic pulmonary infection then spreading onto oral mucosa and skin. [ 2 ] P. brasiliensis naturally resides in soil, and the infection is due to inhalation of its propagules.…”

mentioning

confidence: 99%