Diagnosis and treatment of novel coronavirus pneumonia based on the theory of traditional Chinese medicine

Wang, Shixin; Wang, Yan; Lu, Yubao; Li, Jieyun; Song, Yujun; Nyamgerelt, Munkhtuya; Wang, Xuexi

doi:10.1016/j.joim.2020.04.001

Cited by 91 publications

(79 citation statements)

References 8 publications

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“…Once infected in a host agent or living cell, it produces more viruses using host machinery. With their complexity and diversity, it survives for a long time in the host, bypassing the treatments, and it causes devastating issues such as pandemics [1]. They have RNA or DNA as genetic material with single or double-stranded nucleic acid.…”

Section: Introductionmentioning

confidence: 99%

Bioactive Natural Antivirals: An Updated Review of the Available Plants and Isolated Molecules

et al. 2020

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Viral infections and associated diseases are responsible for a substantial number of mortality and public health problems around the world. Each year, infectious diseases kill 3.5 million people worldwide. The current pandemic caused by COVID-19 has become the greatest health hazard to people in their lifetime. There are many antiviral drugs and vaccines available against viruses, but they have many disadvantages, too. There are numerous side effects for conventional drugs, and active mutation also creates drug resistance against various viruses. This has led scientists to search herbs as a source for the discovery of more efficient new antivirals. According to the World Health Organization (WHO), 65% of the world population is in the practice of using plants and herbs as part of treatment modality. Additionally, plants have an advantage in drug discovery based on their long-term use by humans, and a reduced toxicity and abundance of bioactive compounds can be expected as a result. In this review, we have highlighted the important viruses, their drug targets, and their replication cycle. We provide in-depth and insightful information about the most favorable plant extracts and their derived phytochemicals against viral targets. Our major conclusion is that plant extracts and their isolated pure compounds are essential sources for the current viral infections and useful for future challenges.

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Section: Introductionmentioning

confidence: 99%

Bioactive Natural Antivirals: An Updated Review of the Available Plants and Isolated Molecules

et al. 2020

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“…Therefore, in CM, the combination of the outbreak location and clinical manifestations of COVID-19 patients, shows that the onset of COVID-19 is mostly caused by pathogen of dampness. (6) This leads to the suggestion that herbs with functions of promoting Fei (Lung) and expelling dampness can be applied, and the use of CM has been associated with benefi ts against COVID-19. (7,8) According to the State Council Information Office of China, more than 70,000 COVID-19 patients (91.5% of total confirmed COVID-19 cases in China) were treated with Chinese herbal medicine (CHM) with promising effects.…”

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confidence: 99%

Clinical Practice Guidelines and Experts’ Consensuses for Treatment of Coronavirus Disease 2019 (COVID-19) Patients with Chinese Herbal Medicine: A Systematic Review

Juan

Zhang

et al. 2020

Chin. J. Integr. Med.

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Coronavirus disease 2019 (COVID-19) has rapidly spread throughout the world since December 2019, and it was declared as a pandemic by the World Health Organization (WHO) on 11 March, 2020. (1,2) Infections have been found in more than 200 countries, areas or territories and more than 6 million people were confi rmed with COVID-19, up to June 2020. (3) COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which induces infl ammation and infi ltration in lungs and can lead to systemic inflammatory cytokine storms. (4,5) As of June 2020, no vaccine or specifi c effective drugs have been identifi ed for COVID-19, and supportive treatments are mainly used to manage its symptoms. Through its thousands of years' history of development, Chinese medicine (CM) has acquired abundant clinical experiences and effi cacy in the prevention and treatment of epidemics and endemic diseases. In CM, COVID-19 pertains to a type of "plague" which is caused by evil qi. The characteristics of the evil qi include cold, dampness, and toxin. According to CM theory, Wuhan as center of the epidemic is a city with many lakes and rivers that has high humidity. The climate of Wuhan suggests a relationship with dampness, and patients diagnosed with COVID-19 often have gastrointestinal symptoms such as nausea, vomiting, abdominal distension, and

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“…Thus, auxiliary continuous blood purification could be an essential technology to take care of inflammatory factors, cytokine storm, electrolyte imbalance, and acid-base balance for any COVID-19 patient resulting a reduced renal work-load and a possible recovery of renal function [130,131]. At present, extracorporeal blood purification technology is supplied for severely ill patient with novel coronavirus pneumonia as an auxiliary treatment to improve condition [132].…”

Section: Auxiliary Blood Purification Treatmentmentioning

confidence: 99%

“Tomorrow Never Dies”: Recent Advances in Diagnosis, Treatment, and Prevention Modalities against Coronavirus (COVID-19) amid Controversies

2020

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The outbreak of novel coronavirus disease (2019-nCoV or COVID-19) is responsible for severe health emergency throughout the world. The attack of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is found to be responsible for COVID-19. The World Health Organization has declared the ongoing global public health emergency as a pandemic. The whole world fights against this invincible enemy in various capacities to restore economy, lifestyle, and safe life. Enormous amount of scientific research work(s), administrative strategies, and economic measurements are in place to create a successful step against COVID-19. Furthermore, differences in opinion, facts, and implementation methods laid additional layers of complexities in this battle against survival. Thus, a timely overview of the recent, important, and overall inclusive developments against this pandemic is a pressing need for better understanding and dealing with COVID-19. In this review, we have systematically summarized the epidemiological studies, clinical features, biological properties, diagnostic methods, treatment modalities, and preventive measurements related to COVID-19.

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Diagnosis and treatment of novel coronavirus pneumonia based on the theory of traditional Chinese medicine

Cited by 91 publications

References 8 publications

Bioactive Natural Antivirals: An Updated Review of the Available Plants and Isolated Molecules

Bioactive Natural Antivirals: An Updated Review of the Available Plants and Isolated Molecules

Clinical Practice Guidelines and Experts’ Consensuses for Treatment of Coronavirus Disease 2019 (COVID-19) Patients with Chinese Herbal Medicine: A Systematic Review

“Tomorrow Never Dies”: Recent Advances in Diagnosis, Treatment, and Prevention Modalities against Coronavirus (COVID-19) amid Controversies

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