Background: Fournier's gangrene (FG) is fast-spreading necrotizing gangrene that affects the perineum, perianal, and genital regions, but spares the testicles, bladder, and rectum due to their independent blood supply from the aorta. The purpose of this research is to share our experience managing 32 cases. Patients and method: Between April 2018 and May 2022, researchers from Government Medical College in Nizamabad conducted a prospective cross-sectional study of patients with FG. During the study period, all individuals diagnosed with FG and treated for it were included. Age, sex, hospital stay, premorbid conditions, mobility, mortality, laboratory examinations, and therapies performed are among the data collected from these. Results: A total of 38 patients were seen throughout the study, with four patients being eliminated due to missing data, leaving 32 patients for the final analysis. With a male to female ratio of 15:1, there were 30 (93.75%) males and 2 (6.25%) females.