Diagnosis and Treatment of Forefoot Disorders. Section 4. Tailor's Bunion

ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Intracellular signaling pathways: tyrosine kinase and mTOR inhibitors)

“…In an internal integrated safety analysis of phase 1 and 2 trials evaluating 330 patients with relapsed or refractory CLL who received at least one dose of venetoclax, infections of any grade occurred in approximately 70% of participants [118]. The most common events were upper respiratory tract infection (23%), pneumonia (11%) and nasopharyngitis (10%).…”

“…Pneumonia was the predominant grade 3/4 infection, and there were five cases of infection-attributable death infection (due to septic shock and viral pneumonia). Opportunistic infections occurred in 3.6% of patients and included invasive aspergillosis, PCP, oral and esophageal candidiasis, ocular toxoplasmosis, nocardiosis, herpes pharyngitis and multidermatomal HZ [118]. Venetoclax is a CYP3A substrate, and plasma levels are accordingly modified if coadministered with CYP3A inducers or inhibitors [119].…”

Relationship of Limited Joint Mobility and Foot Deformities with Neurological Examination in Patients with Diabetes

“…Crowded toes were the deformities that associated a hyperextension of the metatarsophalangeal joint with a varus or valgus rotation, which situated the toe above (supraductus) the contralateral toe. Tailor's bunion was considered as a prominence at the lateral aspect of the fi fth metatarsal head with the fi fth toe defl ected to varus [ 28 ] . Statistical analysis was performed with SPSS version 15.0 for Windows (SPSS Inc., Chicago, Illinois).…”

Percutaneous Distal Osteotomy of the Fifth Metatarsal for Correction of Bunionette

“…According to the Coughlin radiographic classification 1 , type-I deformity is an enlargement of the head of the fifth metatarsal, type-II is due to a lateral bowing with a valgus deviation of the fifth metatarsal shaft at its middle or distal level, and type-III deformity is an increase in the intermetatarsal angle between the fourth and the fifth metatarsals. There are many different techniques used to correct deformity of the fifth metatarsal, including soft-tissue procedures, metatarsal osteotomies, or prosthetic implants [1][2][3] . Osteotomies permit complete correction of the deformity with low recurrence rates, and they can be divided into three main groups: proximal, diaphyseal, or distal osteotomies .…”